Cocoa powder and catechins as natural mediators to modify carbon-black based screen-printed electrodes. Application to free and total glutathione detection in blood.
Blood glutathione
Carbon black
Catechins
Cocoa
Nanomaterials
Natural-mediators
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
15 Jan 2020
15 Jan 2020
Historique:
received:
30
06
2019
revised:
08
09
2019
accepted:
11
09
2019
entrez:
10
10
2019
pubmed:
9
10
2019
medline:
20
2
2020
Statut:
ppublish
Résumé
In this work, for the first time, the direct usability of natural products, catechins (CT) and cocoa powder (CO), as electrochemical mediators able to modify a carbon black modified screen-printed electrode (SPE-CB) is proved, and, as proof of applicability, free (GSH) and total glutathione (GSH + GSSG) in blood samples is successfully determined. Noteworthy, the cocoa powder (naturally rich in catechins), dissolved in DMSO, was able to give rise to a useful highly redox-active catechol-quinone surface-confined system onto a carbon black nanoparticles modified screen-printed electrode (SPE-CB-CO - Cocoatrode), giving rise to a similar behaviour obtained with pure catechins (SPE-CB-CT). The electrodeposition process has been carefully studied, the resulting immobilized natural mediator (obtained using both CT and CO) features investigated, and the performance of the resulting sensors (SPE-CB-CT and Cocoatrode) tested and compared. Both modified electrodes (SPE-CB-CT and Cocoatrode) have a good inter-electrodes precision (RSD i
Identifiants
pubmed: 31594572
pii: S0039-9140(19)30982-8
doi: 10.1016/j.talanta.2019.120349
pii:
doi:
Substances chimiques
Soot
0
Catechin
8R1V1STN48
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
120349Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.