[Intraoperative fluorescence angiography in colorectal surgery].

Intraoperative Fluoreszenzangiographie in der kolorektalen Chirurgie.

Journal

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
ISSN: 1433-0385
Titre abrégé: Chirurg
Pays: Germany
ID NLM: 16140410R

Informations de publication

Date de publication:
Nov 2019
Historique:
pubmed: 18 10 2019
medline: 20 11 2019
entrez: 18 10 2019
Statut: ppublish

Résumé

Fluorescence angiography with indocyanine green (ICG-FA) is frequently used in colorectal surgery to assess the blood perfusion in the region of an anastomosis. Previous studies with ICG-FA in both open and laparoscopic surgery could show a low rate of anastomotic leakage, e.g. the PILLAR II study with a leakage rate of 1.4%. This article presents own results, the current status of ICG-FA and the fields of application. The aim of the study was to analyze whether the results obtained so far with ICG-FA are sufficient to recommend an extended use of this relatively new method in colorectal surgery. From July 2009 to June 2019 a total of 378 colorectal resections (280 colon resections and 98 rectal resections) with intraoperative examination of the anastomosis using ICG-FA were performed. In 13 patients (3.4%) there was reduced intraoperative perfusion, which led to a change in the operative procedure (resection of the anastomosis and new anastomosis, colostomy). The total anastomotic leakage rate was 3.7% with 8 leaks in the colon (2.9%) and 6 in the rectum (6.1%). Without the intraoperative change in 13 patients the rate of leakages could have increased to 7.1% (27/378). The use of ICG-FA in the group of patients studied potentially led to a reduction of the leakage rate by 48%. Current publications show similar results with a potential decrease in the rate of anastomotic leaks in colorectal surgery. The results show a very low rate of anastomotic leakage when using ICG-FA. These results are promising in colorectal surgery but controlled randomized studies are lacking and should be carried out before final recommendations can be given.

Sections du résumé

BACKGROUND BACKGROUND
Fluorescence angiography with indocyanine green (ICG-FA) is frequently used in colorectal surgery to assess the blood perfusion in the region of an anastomosis. Previous studies with ICG-FA in both open and laparoscopic surgery could show a low rate of anastomotic leakage, e.g. the PILLAR II study with a leakage rate of 1.4%. This article presents own results, the current status of ICG-FA and the fields of application.
OBJECTIVE OBJECTIVE
The aim of the study was to analyze whether the results obtained so far with ICG-FA are sufficient to recommend an extended use of this relatively new method in colorectal surgery.
MATERIAL AND METHODS METHODS
From July 2009 to June 2019 a total of 378 colorectal resections (280 colon resections and 98 rectal resections) with intraoperative examination of the anastomosis using ICG-FA were performed. In 13 patients (3.4%) there was reduced intraoperative perfusion, which led to a change in the operative procedure (resection of the anastomosis and new anastomosis, colostomy).
RESULTS RESULTS
The total anastomotic leakage rate was 3.7% with 8 leaks in the colon (2.9%) and 6 in the rectum (6.1%). Without the intraoperative change in 13 patients the rate of leakages could have increased to 7.1% (27/378). The use of ICG-FA in the group of patients studied potentially led to a reduction of the leakage rate by 48%. Current publications show similar results with a potential decrease in the rate of anastomotic leaks in colorectal surgery.
CONCLUSION CONCLUSIONS
The results show a very low rate of anastomotic leakage when using ICG-FA. These results are promising in colorectal surgery but controlled randomized studies are lacking and should be carried out before final recommendations can be given.

Identifiants

pubmed: 31620821
doi: 10.1007/s00104-019-01042-4
pii: 10.1007/s00104-019-01042-4
doi:

Substances chimiques

Indocyanine Green IX6J1063HV

Types de publication

Journal Article Review

Langues

ger

Sous-ensembles de citation

IM

Pagination

887-890

Références

Colorectal Dis. 2015 Oct;17 Suppl 3:16-21
pubmed: 26394738
Tech Coloproctol. 2018 Jul;22(7):535-540
pubmed: 30097803
Surg Endosc. 2017 Apr;31(4):1836-1840
pubmed: 27553790
Int J Colorectal Dis. 2006 May;21(4):332-8
pubmed: 16133007
J Am Coll Surg. 2015 Jan;220(1):82-92.e1
pubmed: 25451666

Auteurs

T Carus (T)

Klinik für Allgemein-, Visceral- und Gefäßchirurgie, Elisabeth-Krankenhaus, Klosterstr. 4, 49832, Thuine, Deutschland. thomas.carus@niels-stensen-kliniken.de.
Klinik für Allgemein‑, Visceral- und Gefäßchirurgie, Asklepios Westklinikum Hamburg, Hamburg, Deutschland. thomas.carus@niels-stensen-kliniken.de.

P Pick (P)

Klinik für Allgemein‑, Visceral- und Gefäßchirurgie, Asklepios Westklinikum Hamburg, Hamburg, Deutschland.

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