Factors associated with non-beneficial treatments in end of life hospital admissions: a multicentre retrospective cohort study in Australia.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
04 11 2019
Historique:
entrez: 7 11 2019
pubmed: 7 11 2019
medline: 24 10 2020
Statut: epublish

Résumé

To quantitatively assess the factors associated with non-beneficial treatments (NBTs) in hospital admissions at the end of life. Retrospective multicentre cohort study. Three large, metropolitan tertiary hospitals in Australia. 831 adult patients who died as inpatients following admission to the study hospitals over a 6-month period in 2012. Odds ratios (ORs) of NBT derived from logistic regression models. Overall, 103 (12.4%) admissions involved NBTs. Admissions that involved conflict within a patient's family (OR 8.9, 95% CI 4.1 to 18.9) or conflict within the medical team (OR 6.5, 95% CI 2.4 to 17.8) had the strongest associations with NBTs in the all subsets regression model. A positive association was observed in older patients, with each 10-year increment in age increasing the likelihood of NBT by approximately 50% (OR 1.5, 95% CI 1.2 to 1.9). There was also a statistically significant hospital effect. This paper presents the first statistical modelling results to assess the factors associated with NBT in hospital, beyond an intensive care setting. Our findings highlight potential areas for intervention to reduce the likelihood of NBTs.

Identifiants

pubmed: 31690607
pii: bmjopen-2019-030955
doi: 10.1136/bmjopen-2019-030955
pmc: PMC6858125
doi:

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e030955

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Hannah Elizabeth Carter (HE)

Australian Centre for Health Services Innovation, Institute of Health and Biomedical Innovation, School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia hannah.carter@qut.edu.au.

Xing Ju Lee (XJ)

Australian Centre for Health Services Innovation, Institute of Health and Biomedical Innovation, School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.

Cindy Gallois (C)

School of Psychology, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.

Sarah Winch (S)

Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

Leonie Callaway (L)

Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Royal Brisbane and Womens Hospital, Herston, Queensland, Australia.

Lindy Willmott (L)

Australian Centre for Health Law Research, Faculty of Law, Queensland University of Technology, Brisbane, Queensland, Australia.

Ben White (B)

Australian Centre for Health Law Research, Faculty of Law, Queensland University of Technology, Brisbane, Queensland, Australia.

Malcolm Parker (M)

Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

Eliana Close (E)

Australian Centre for Health Law Research, Faculty of Law, Queensland University of Technology, Brisbane, Queensland, Australia.

Nicholas Graves (N)

Australian Centre for Health Services Innovation, Institute of Health and Biomedical Innovation, School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Duke-NUS Medical School, Singapore, Singapore.

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