Recent Trends in the Application of Chromatographic Techniques in the Analysis of Luteolin and Its Derivatives.
chromatography
hyphenated techniques
luteolin
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
12 11 2019
12 11 2019
Historique:
received:
01
10
2019
revised:
07
11
2019
accepted:
08
11
2019
entrez:
16
11
2019
pubmed:
16
11
2019
medline:
19
8
2020
Statut:
epublish
Résumé
Luteolin is a flavonoid often found in various medicinal plants that exhibits multiple biological effects such as antioxidant, anti-inflammatory and immunomodulatory activity. Commercially available medicinal plants and their preparations containing luteolin are often used in the treatment of hypertension, inflammatory diseases, and even cancer. However, to establish the quality of such preparations, appropriate analytical methods should be used. Therefore, the present paper provides the first comprehensive review of the current analytical methods that were developed and validated for the quantitative determination of luteolin and its C- and O-derivatives including orientin, isoorientin, luteolin 7-O-glucoside and others. It provides a systematic overview of chromatographic analytical techniques including thin layer chromatography (TLC), high performance thin layer chromatography (HPTLC), liquid chromatography (LC), high performance liquid chromatography (HPLC), gas chromatography (GC) and counter-current chromatography (CCC), as well as the conditions used in the determination of luteolin and its derivatives in plant material.
Identifiants
pubmed: 31726801
pii: biom9110731
doi: 10.3390/biom9110731
pmc: PMC6921003
pii:
doi:
Substances chimiques
Flavones
0
Flavonoids
0
Glucosides
0
luteolin-7-glucoside
98J6XDS46I
homoorientin
A37342TIX1
orientin
IAX93XCW6C
Luteolin
KUX1ZNC9J2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
All authors state that they are free of any conflicts of interest related to this paper.
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