Tumor genetic heterogeneity analysis of chronic sun-damaged melanoma.
Adolescent
Adult
Aged
Aged, 80 and over
Carcinoma in Situ
/ genetics
Chronic Disease
Cohort Studies
DNA Copy Number Variations
/ genetics
Female
Genetic Heterogeneity
High-Throughput Nucleotide Sequencing
Humans
Male
Melanoma
/ genetics
Middle Aged
Mutation
/ genetics
Neoplasm Invasiveness
Oncogenes
Sunlight
/ adverse effects
Transcription, Genetic
Young Adult
chronic sun damage
heterogeneity
in situ
invasive
melanoma
Journal
Pigment cell & melanoma research
ISSN: 1755-148X
Titre abrégé: Pigment Cell Melanoma Res
Pays: England
ID NLM: 101318927
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
19
09
2019
revised:
21
11
2019
accepted:
29
11
2019
pubmed:
8
12
2019
medline:
5
2
2021
entrez:
8
12
2019
Statut:
ppublish
Résumé
Chronic sun-damaged (CSD) melanoma represents 10%-20% of cutaneous melanomas and is characterized by infrequent BRAF V600E mutations and high mutational load. However, the order of genetic events or the extent of intra-tumor heterogeneity (ITH) in CSD
Identifiants
pubmed: 31811783
doi: 10.1111/pcmr.12851
pmc: PMC7217060
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
480-489Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2019 The Authors. Pigment Cell & Melanoma Research published by John Wiley & Sons Ltd.
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