Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex.

Acetylcholinesterase / chemistry Alkaloids / chemistry Benzylisoquinolines / chemistry Berberine / analogs & derivatives Cholinesterase Inhibitors / chemistry Coptis chinensis Drug Combinations Drug Synergism Drugs, Chinese Herbal / chemistry Medicine, Chinese Traditional Molecular Docking Simulation Phellodendron / chemistry Plant Extracts / chemistry Stephania tetrandra / chemistry
acetylcholinesterase berberine coptisine fangchinoline synergistic effect

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
13 Dec 2019
Historique:
received: 29 10 2019
revised: 30 11 2019
accepted: 10 12 2019
entrez: 19 12 2019
pubmed: 19 12 2019
medline: 15 5 2020
Statut: epublish

Résumé

Alkaloids having acetylcholinesterase (AChE) inhibitory activity are commonly found in traditional Chinese medicine (TCM); for example, berberine from

Identifiants

DOI: 10.3390/molecules24244567 PMID: 31847089 PMC: PMC6943709
pubmed: 31847089
pii: molecules24244567
doi: 10.3390/molecules24244567
pmc: PMC6943709
pii:
doi:

Substances chimiques

Alkaloids 0
Benzylisoquinolines 0
Cholinesterase Inhibitors 0
Drug Combinations 0
Drugs, Chinese Herbal 0
Plant Extracts 0
coptisine 0GCL71VN14
Berberine 0I8Y3P32UF
fangchinoline 953592C3ZB
Coptidis rhizoma extract CXS4LJR7EL
Acetylcholinesterase EC 3.1.1.7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : China Postdoctoral Science Foundation
ID : 2019M653087
Organisme : Science, Technology and Innovation Commission of Shenzhen Municipality
ID : JCYJ20170413173747440
Organisme : Science, Technology and Innovation Commission of Shenzhen Municipality
ID : JCYJ20160229205812004
Organisme : Science, Technology and Innovation Commission of Shenzhen Municipality
ID : ZDSYS201707281432317

Références

Front Mol Neurosci. 2013 Jan 09;5:101
pubmed: 23316131
J Pharm Biomed Anal. 2012 Nov;70:671-9
pubmed: 22704738
Neurosci Lett. 1995 Dec 1;201(1):49-52
pubmed: 8830310
J Mol Biol. 1997 Sep 26;272(3):348-61
pubmed: 9325095
Molecules. 2011 Aug 09;16(8):6732-40
pubmed: 21829148
Prog Neurobiol. 2004 Dec;74(6):323-49
pubmed: 15649580
Chin Med. 2007 Nov 29;2:12
pubmed: 18045504
Comput Biol Chem. 2018 Aug;75:178-195
pubmed: 29883916
Insect Sci. 2013 Apr;20(2):254-60
pubmed: 23955865
J Alzheimers Dis. 2015;43(1):291-302
pubmed: 25079795
Planta Med. 2010 Oct;76(14):1530-5
pubmed: 20354951
Curr Top Med Chem. 2006;6(6):579-95
pubmed: 16712493
Proc Natl Acad Sci U S A. 1988 Feb;85(4):1262-6
pubmed: 3422489
Neurosci Bull. 2008 Apr;24(2):105-9
pubmed: 18369390
Biol Pharm Bull. 2009 Aug;32(8):1433-8
pubmed: 19652386
Molecules. 2016 Aug 31;21(9):
pubmed: 27589716
J Neural Transm (Vienna). 2005 Jan;112(1):149-62
pubmed: 15599613
J Mol Neurosci. 2014 Jul;53(3):511-6
pubmed: 24793543
Arch Pharm Res. 2002 Jun;25(3):349-56
pubmed: 12135109
Curr Neuropharmacol. 2013 Jul;11(4):388-413
pubmed: 24381530
J Mol Neurosci. 2014 Jul;53(3):446-53
pubmed: 24318838
Curr Alzheimer Res. 2018;15(11):1045-1052
pubmed: 29962345
J Cell Biochem. 2018 Jul;119(7):5598-5608
pubmed: 29405440
Transl Neurodegener. 2013 Feb 28;2(1):6
pubmed: 23445907
Immunity. 2009 Dec 18;31(6):965-73
pubmed: 20005135
J Neural Transm (Vienna). 2006 Nov;113(11):1625-44
pubmed: 17039298
Indian J Biochem Biophys. 2013 Apr;50(2):120-5
pubmed: 23720886
Phytomedicine. 2014 Jul-Aug;21(8-9):1110-9
pubmed: 24856768
PLoS One. 2012;7(8):e43990
pubmed: 22952840
Neurochem Res. 2003 Apr;28(3-4):515-22
pubmed: 12675140
Pediatr Blood Cancer. 2012 Sep;59(3):540-7
pubmed: 22238217
Biochem Pharmacol. 1961 Jul;7:88-95
pubmed: 13726518
J Mol Model. 2006 Mar;12(4):390-7
pubmed: 16404617
Pharmacol Biochem Behav. 2005 May;81(1):89-99
pubmed: 15882896
Planta Med. 2006 Oct;72(13):1227-31
pubmed: 16902872
J Psychiatry Neurosci. 2004 Nov;29(6):427-41
pubmed: 15644984
Cancer Res. 2010 Jan 15;70(2):440-6
pubmed: 20068163
Neuron. 1996 Apr;16(4):881-91
pubmed: 8608006
J Cell Biochem. 2010 Jun 1;110(3):697-705
pubmed: 20512929
Structure. 1999 Mar 15;7(3):297-307
pubmed: 10368299
J Neurochem. 2012 Jan;120 Suppl 1:iii-iv
pubmed: 22182264
Acta Clin Belg. 2008 Sep-Oct;63(5):339-42
pubmed: 19186568
Neuropsychiatr Dis Treat. 2016 Oct 03;12:2509-2520
pubmed: 27757035
Neurobiol Aging. 2003 Oct;24(6):777-87
pubmed: 12927760
PLoS One. 2014 Mar 26;9(3):e92954
pubmed: 24671102
Neurochem Int. 2009 Jul;54(8):506-12
pubmed: 19428795
Brain Behav Immun. 2009 Jan;23(1):41-5
pubmed: 18639629
Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(3):602-607
pubmed: 30989929
J Ethnopharmacol. 2000 Feb;69(2):173-9
pubmed: 10687873
Neurochem Int. 2015 Oct;89:260-70
pubmed: 26220901
Evid Based Complement Alternat Med. 2011;2011:307548
pubmed: 19131392
Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1943-8
pubmed: 19894540

Auteurs

Xiang-Peng Kong (XP)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Institute of Pharmaceutical & Food Engineering, Shanxi University of Chinese Medicine, 121 Daxue Road, Yuci District, Jinzhong 030619, China.

Etta Y L Liu (EYL)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Zhi-Cong Chen (ZC)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Miranda Li Xu (ML)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Anna X D Yu (AXD)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Qi-Yun Wu (QY)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Ying-Jie Xia (YJ)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Ran Duan (R)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Tina T X Dong (TTX)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Karl W K Tsim (KWK)

Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Articles similaires

Decoding the genomic terrain: functional insights into 14 chemosensory proteins in whitefly Bemisia tabaci Asia II-1.

M N Rudra Gouda, Sabtharishi Subramanian
1.00
Animals Hemiptera Insect Proteins Phylogeny Insecticides

Influencing factors, evolution, and strategies for improving the quality of traditional Chinese medicine patents: an empirical study based on patent invalidation cases.

Xin Li
1.00
Medicine, Chinese Traditional Patents as Topic Humans

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Muhammad Atif, Humaira Zafar, Atia-Tul- Wahab et al.
1.00
Fucosyltransferases Drug Repositioning Molecular Docking Simulation Molecular Dynamics Simulation Humans

Pesticide Exposure and Its Association with Parkinson's Disease: A Case-Control Analysis.

Ali Samareh, Hossein Pourghadamyari, Mohammad Hadi Nemtollahi et al.
1.00
Humans Pesticides Case-Control Studies Male Female

Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Cholinesterases › Acetylcholinesterase › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoquinoléines › Benzylisoquinoléines › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques avec 4 noyaux ou plus › Alcaloïdes de type berbérine › Berbérine › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Anticholinestérasiques › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Ranunculales › Ranonculaceae › Coptis › Coptis chinensis › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Préparations pharmaceutiques › Association médicamenteuse › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Interactions médicamenteuses › Synergie des médicaments › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Préparations pharmaceutiques › Médicaments issus de plantes chinoises › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Sciences sociales › Anthropologie › Anthropologie culturelle › Médecine traditionnelle › Médecine traditionnelle d'Asie orientale › Médecine traditionnelle chinoise › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rutaceae › Phellodendron › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Synergistic Inhibition of Acetylcholinesterase...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Menispermaceae › Stephania › Stephania tetrandra › Synergistic Inhibition of Acetylcholinesterase...