Mechanistic insights into controlled depolymerization of Chitosan using H-Mordenite.


Journal

Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156

Informations de publication

Date de publication:
15 Feb 2020
Historique:
received: 05 08 2019
revised: 25 10 2019
accepted: 09 11 2019
entrez: 1 1 2020
pubmed: 1 1 2020
medline: 5 6 2020
Statut: ppublish

Résumé

Kinetics of chitosan depolymerization were studied in dilute acetic acid solution, in presence of H-Mordenite (H-MOR). Rate constants for chitosan depolymerization were determined by measurement of molecular weight, using Gel permeation Chromatography (GPC). Depolymerization rate of chitosan was altered in presence of an acidic, porous material like H-MOR. Maximum concentration of H-MOR studied during process led to minimal increase in energy of activation, from 20.54 kJ/moL to 23.25 kJ/moL. Infra-red spectroscopy, adsorption studies and rheological assessment indicated adsorption /grafting of chitosan onto porous H-MOR surface as the possible mechanism for facilitation of the depolymerization process. Under extreme conditions investigated during process optimization, H-MOR resulted in a three-fold reduction in 5-Hydroxy Methyl Furfural (5-HMF) formation and over ten times decrease in glucosamine content, as compared to reactions conducted without H-MOR. Therefore, presence of H-MOR is imperative to cleave chitosan in controlled manner and obtain products of desired molecular weight, with fewer impurities.

Identifiants

pubmed: 31887872
pii: S0144-8617(19)31268-8
doi: 10.1016/j.carbpol.2019.115600
pii:
doi:

Substances chimiques

Acids 0
Aluminum Silicates 0
mordenite 12445-20-4
Chitosan 9012-76-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115600

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

A Pandit (A)

Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai-19, India.

C Deshpande (C)

Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai-19, India.

S Patil (S)

Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai-19, India.

R Jain (R)

Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai-19, India. Electronic address: rd.jain@ictmumbai.edu.in.

P Dandekar (P)

Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai-19, India. Electronic address: pd.jain@ictmumbai.edu.in.

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Classifications MeSH