A Redox-Sensitive Thiol in Wis1 Modulates the Fission Yeast Mitogen-Activated Protein Kinase Response to H

Cysteine / chemistry Gene Expression Regulation, Fungal / physiology Hydrogen Peroxide / pharmacology Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors Mitogen-Activated Protein Kinases / metabolism Oxidation-Reduction Protein Kinase Inhibitors / pharmacology Schizosaccharomyces / metabolism Schizosaccharomyces pombe Proteins / antagonists & inhibitors Sequence Alignment
Schizosaccharomyces pombe Sty1 cysteine oxidation stress signaling

Journal

Molecular and cellular biology
ISSN: 1098-5549
Titre abrégé: Mol Cell Biol
Pays: United States
ID NLM: 8109087

Informations de publication

Date de publication:
16 03 2020
Historique:
received: 30 07 2019
accepted: 03 01 2020
pubmed: 15 1 2020
medline: 28 7 2020
entrez: 15 1 2020
Statut: epublish

Résumé

Oxidation of a highly conserved cysteine (Cys) residue located in the kinase activation loop of mitogen-activated protein kinase kinases (MAPKK) inactivates mammalian MKK6. This residue is conserved in the fission yeast

Identifiants

DOI: 10.1128/MCB.00346-19 PMID: 31932483 PMC: PMC7076255
pubmed: 31932483
pii: MCB.00346-19
doi: 10.1128/MCB.00346-19
pmc: PMC7076255
pii:
doi:

Substances chimiques

Protein Kinase Inhibitors 0
Schizosaccharomyces pombe Proteins 0
Hydrogen Peroxide BBX060AN9V
Mitogen-Activated Protein Kinases EC 2.7.11.24
sty1 protein, S pombe EC 2.7.11.24
Mitogen-Activated Protein Kinase Kinases EC 2.7.12.2
wis1 protein, S pombe EC 2.7.12.2
Cysteine K848JZ4886

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2020 Sjölander et al.

Références

Mol Genet Genomics. 2006 Dec;276(6):495-502
pubmed: 17043891
Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1775-89
pubmed: 16987031
Mol Microbiol. 2014 May;92(4):777-96
pubmed: 24666325
Genes Dev. 1995 Sep 1;9(17):2117-30
pubmed: 7657164
J Biol Chem. 2002 Sep 6;277(36):33411-21
pubmed: 12080074
Mol Biol Cell. 2000 Apr;11(4):1169-81
pubmed: 10749922
Cell. 2002 May 3;109(3):275-82
pubmed: 12015977
Commun Integr Biol. 2013 Sep 1;6(5):e25020
pubmed: 24255738
J Mol Biol. 2002 Jul 12;320(3):597-608
pubmed: 12096912
J Biol Chem. 2008 May 2;283(18):12373-86
pubmed: 18326045
Mol Biol Cell. 2013 Apr;24(7):1083-92
pubmed: 23389634
J Biol Chem. 1999 Sep 10;274(37):26563-71
pubmed: 10473620
Science. 2007 Sep 7;317(5843):1393-7
pubmed: 17717153
FEBS Lett. 2001 Jul 27;502(1-2):21-4
pubmed: 11478941
Eur J Med Chem. 2014 Oct 6;85:127-38
pubmed: 25078316
Nat Struct Mol Biol. 2004 Dec;11(12):1192-7
pubmed: 15543157
Chem Biol. 2013 Jun 20;20(6):745-6
pubmed: 23790484
Methods Enzymol. 1991;194:795-823
pubmed: 2005825
Mol Biol Cell. 2002 Mar;13(3):805-16
pubmed: 11907263
Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7686-9
pubmed: 7644477
Mol Biol Cell. 2001 Feb;12(2):407-19
pubmed: 11179424
J Med Chem. 2006 Oct 19;49(21):6177-96
pubmed: 17034125
Nat Protoc. 2014 Sep;9(9):2100-22
pubmed: 25101824
Mol Cell. 2016 Aug 18;63(4):553-566
pubmed: 27540856
J Biol Chem. 2002 Nov 8;277(45):43505-11
pubmed: 12189155
Mol Biol Cell. 1998 Jun;9(6):1339-49
pubmed: 9614178
Mol Cell. 2004 Jul 2;15(1):129-39
pubmed: 15225554
Mol Biol Cell. 2002 Aug;13(8):2651-63
pubmed: 12181336
Genes Dev. 1996 Sep 15;10(18):2289-301
pubmed: 8824588
Mol Biol Cell. 1998 Aug;9(8):2325-35
pubmed: 9693384
Chem Biol Drug Des. 2016 Oct;88(4):485-97
pubmed: 27115708
Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8875-80
pubmed: 15956211
Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20974-9
pubmed: 21078955
Mol Cell Biol. 1996 Jun;16(6):2870-7
pubmed: 8649397
J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):297-301
pubmed: 23856010
Cell Metab. 2019 Dec 3;30(6):1152-1170.e13
pubmed: 31735592
Genes Dev. 1999 Jul 1;13(13):1653-63
pubmed: 10398679
J Biol Chem. 2005 Jan 28;280(4):2750-8
pubmed: 15533936
Curr Opin Struct Biol. 2016 Aug;39:106-114
pubmed: 27423114
Nat Rev Mol Cell Biol. 2007 Oct;8(10):813-24
pubmed: 17848967
J Med Chem. 2012 May 24;55(10):4872-6
pubmed: 22559926
J Biochem. 1998 Jun;123(6):1048-54
pubmed: 9603992
EMBO J. 2012 Feb 1;31(3):563-75
pubmed: 22139357
Nat Commun. 2015 Aug 10;6:7920
pubmed: 26258640
Mol Cell. 2008 Apr 11;30(1):108-13
pubmed: 18406331
Yeast. 2005 Oct 15;22(13):1013-9
pubmed: 16200533
Genes Dev. 1997 Apr 15;11(8):1008-22
pubmed: 9136929
Nat Chem Biol. 2011 Dec 11;8(1):57-64
pubmed: 22158416
Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1555-66
pubmed: 25839999
J Med Chem. 2004 Mar 25;47(7):1750-9
pubmed: 15027866
Nature. 1995 Dec 14;378(6558):739-43
pubmed: 7501024
J Biol Chem. 2010 Oct 22;285(43):32818-23
pubmed: 20729203

Auteurs

Johanna J Sjölander (JJ)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Agata Tarczykowska (A)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Cecilia Picazo (C)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Chalmers University of Technology, Department of Biology and Biological Engineering, Gothenburg, Sweden.

Itziar Cossio (I)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Itedale Namro Redwan (IN)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Chunxia Gao (C)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Carlos Solano (C)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Michel B Toledano (MB)

Oxidative Stress and Cancer Laboratory, Integrative Biology and Molecular Genetics Unit, CEA Saclay, Gif-sur-Yvette, France.

Morten Grøtli (M)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.

Mikael Molin (M)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden mikael.molin@chalmers.se per.sunnerhagen@cmb.gu.se.
Chalmers University of Technology, Department of Biology and Biological Engineering, Gothenburg, Sweden.

Per Sunnerhagen (P)

University of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden mikael.molin@chalmers.se per.sunnerhagen@cmb.gu.se.
ORCID: 0000-0002-0967-8729

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Cystéine › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes fongiques › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › Peroxyde d'hydrogène › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-tyrosine kinases › Mitogen-Activated Protein Kinase Kinases › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Mitogen-Activated Protein Kinases › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Schizosaccharomyces › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Protéines de Schizosaccharomyces pombe › A Redox-Sensitive Thiol in Wis1 Modulates the...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Alignement de séquences › A Redox-Sensitive Thiol in Wis1 Modulates the...