Underweight is associated with inferior short and long-term outcomes after MitraClip implantation: Results from the German TRAnscatheter mitral valve interventions (TRAMI) registry.
Cardiac Catheterization
/ methods
Echocardiography
Follow-Up Studies
Germany
/ epidemiology
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
/ methods
Hospital Mortality
/ trends
Incidence
Mitral Valve
/ diagnostic imaging
Mitral Valve Insufficiency
/ complications
Postoperative Complications
/ epidemiology
Registries
Retrospective Studies
Risk Factors
Survival Rate
/ trends
Thinness
/ complications
Time Factors
Treatment Outcome
Journal
American heart journal
ISSN: 1097-6744
Titre abrégé: Am Heart J
Pays: United States
ID NLM: 0370465
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
20
08
2019
accepted:
21
12
2019
pubmed:
6
2
2020
medline:
1
5
2020
entrez:
5
2
2020
Statut:
ppublish
Résumé
Underweight and obesity represent classical risk factors for adverse outcome in patients treated for cardiovascular disease. The current analysis examines the impact of underweight, overweight and obesity on intra-hospital, short and long-term outcomes in patients treated by MitraClip therapy. From August 2010 until July 2013, 799 patients (age 75.3 ± 8.6 years, male gender 60.7%, median logistic EuroSCORE 20% [12; 31], functional mitral regurgitation (MR): 69.3%) were prospectively enrolled into the multicenter German Transcatheter Mitral Valve Interventions registry. Patients were stratified according to body mass index (BMI) into 4 groups: BMI <20 kg/m Compared to other weight groups, underweight patients undergoing MitraClip implantation are exposed to increased rates of procedural failure, bleeding and low cardiac output as well as increased short- and long-term mortality rates and should therefore be carefully discussed in the heart-team.
Sections du résumé
BACKGROUND
Underweight and obesity represent classical risk factors for adverse outcome in patients treated for cardiovascular disease.
AIMS
The current analysis examines the impact of underweight, overweight and obesity on intra-hospital, short and long-term outcomes in patients treated by MitraClip therapy.
METHODS AND RESULTS
From August 2010 until July 2013, 799 patients (age 75.3 ± 8.6 years, male gender 60.7%, median logistic EuroSCORE 20% [12; 31], functional mitral regurgitation (MR): 69.3%) were prospectively enrolled into the multicenter German Transcatheter Mitral Valve Interventions registry. Patients were stratified according to body mass index (BMI) into 4 groups: BMI <20 kg/m
CONCLUSIONS
Compared to other weight groups, underweight patients undergoing MitraClip implantation are exposed to increased rates of procedural failure, bleeding and low cardiac output as well as increased short- and long-term mortality rates and should therefore be carefully discussed in the heart-team.
Identifiants
pubmed: 32018204
pii: S0002-8703(20)30007-7
doi: 10.1016/j.ahj.2019.12.022
pii:
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
73-82Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.