Antidiarrheal activity of farnesol in rodents: Pharmacological actions and molecular docking.
Animals
Antidiarrheals
/ pharmacology
Castor Oil
Chlorides
/ metabolism
Cholera Toxin
Diarrhea
/ chemically induced
Dinoprostone
Farnesol
/ pharmacology
Female
Gastrointestinal Motility
/ drug effects
Intestinal Absorption
/ drug effects
Intestinal Mucosa
/ metabolism
Intestinal Secretions
/ metabolism
Male
Mice
Molecular Docking Simulation
Naloxone
/ pharmacology
Narcotic Antagonists
/ pharmacology
Receptors, Cell Surface
/ metabolism
Castor oil
Cholera
Farnesol
Gastrointestinal transit
Sesquiterpene
Journal
European journal of pharmacology
ISSN: 1879-0712
Titre abrégé: Eur J Pharmacol
Pays: Netherlands
ID NLM: 1254354
Informations de publication
Date de publication:
05 May 2020
05 May 2020
Historique:
received:
30
08
2019
revised:
31
01
2020
accepted:
03
02
2020
pubmed:
8
2
2020
medline:
2
12
2020
entrez:
8
2
2020
Statut:
ppublish
Résumé
Diarrhea is a condition in which the individual has about three or more daily bowel movements, followed by changes in stool consistency. It is currently considered as one of the worst public health problems due to the number of cases and deaths involved and difficulty of treatment. Thus, the use of natural products is an alternative for new treatments. Among these possibilities is Farnesol (C
Identifiants
pubmed: 32032601
pii: S0014-2999(20)30078-9
doi: 10.1016/j.ejphar.2020.172986
pii:
doi:
Substances chimiques
Antidiarrheals
0
Chlorides
0
Narcotic Antagonists
0
Receptors, Cell Surface
0
ganglioside receptor
0
Naloxone
36B82AMQ7N
Farnesol
4602-84-0
Castor Oil
8001-79-4
Cholera Toxin
9012-63-9
Dinoprostone
K7Q1JQR04M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
172986Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of competing interest None.