Trends in MitraClip, mitral valve repair, and mitral valve replacement from 2000 to 2016.


Journal

The Journal of thoracic and cardiovascular surgery
ISSN: 1097-685X
Titre abrégé: J Thorac Cardiovasc Surg
Pays: United States
ID NLM: 0376343

Informations de publication

Date de publication:
08 2021
Historique:
received: 22 05 2019
revised: 29 11 2019
accepted: 05 12 2019
pubmed: 25 2 2020
medline: 3 8 2021
entrez: 25 2 2020
Statut: ppublish

Résumé

The dissemination of mitral valve repair as the first-line treatment and the introduction of MitraClip for patients who have a prohibitive risk for surgery have changed the landscape of mitral valve intervention. The aim of this study is to provide current and generalizable data regarding the trend of mitral valve interventions and outcomes from 2000 to 2016. Patients ≥18 years of age who underwent mitral-valve interventions were identified using the National Inpatient Sample database. National estimates were generated by means of discharge weights; comorbid conditions were identified using Elixhauser methods. All trends were analyzed with JoinPoint software. A total of 656,030 mitral valve interventions (298,102 mitral valve replacement, 349,053 mitral valve repair, and 8875 MitraClip) were assessed. No changes in rate of procedures (per 100,000 people in the United States) were observed over this period (annual percent change, -0.4; 95% confidence limit, -1.1 to 0.3; P = .3). From 2000 to 2010, the number of replacements decreased by 5.6% per year (P < .001), whereas repair increased by 8.4% per year from 2000 to 2006 (P < .001). MitraClip procedures increased by 84.4% annually from 2013 to 2016 (P < .001). The burden of comorbidities increased throughout the study for all groups, with the greatest score for MitraClip recipients. Overall, length of stay has decreased for all interventions, most significantly for MitraClip. In-hospital mortality decreased from 8.5% to 3.7% for all interventions, with MitraClip having the most substantial decrease from 3.6% to 1.5%. Over a 17-year period, mitral-valve interventions were associated with improved outcomes despite being applied to an increasingly sicker population.

Identifiants

pubmed: 32089343
pii: S0022-5223(20)30182-3
doi: 10.1016/j.jtcvs.2019.12.097
pmc: PMC7957952
mid: NIHMS1675751
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Video-Audio Media

Langues

eng

Sous-ensembles de citation

IM

Pagination

551-562.e4

Subventions

Organisme : NHLBI NIH HHS
ID : U01 HL088942
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2020 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

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Auteurs

Selena Zhou (S)

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

Natalia Egorova (N)

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: natalia.egorova@mountsinai.org.

Gil Moskowitz (G)

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

Gennaro Giustino (G)

Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY.

Gorav Ailawadi (G)

Section of Adult Cardiac Surgery, University of Virginia, Charlottesville, Va.

Michael A Acker (MA)

Division of Cardiovascular Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.

Marc Gillinov (M)

Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.

Alan Moskowitz (A)

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

Annetine Gelijns (A)

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

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