Candida bloodstream infection in patients with systemic autoimmune diseases.
Adrenal Cortex Hormones
/ adverse effects
Adult
Aged
Aged, 80 and over
Arthritis, Rheumatoid
/ complications
Autoimmune Diseases
/ complications
Candida
/ classification
Candidemia
/ epidemiology
Comorbidity
Cross Infection
/ epidemiology
Female
France
/ epidemiology
Humans
Immunocompromised Host
Immunosuppressive Agents
/ adverse effects
Male
Methotrexate
/ adverse effects
Middle Aged
Opportunistic Infections
/ epidemiology
Retrospective Studies
Spain
/ epidemiology
Survival Rate
Candidemia
Corticosteroid therapy
Immunosuppressive therapy
Systemic autoimmune disease
Journal
Medecine et maladies infectieuses
ISSN: 1769-6690
Titre abrégé: Med Mal Infect
Pays: France
ID NLM: 0311416
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
30
06
2019
revised:
09
12
2019
accepted:
29
01
2020
pubmed:
3
3
2020
medline:
25
8
2021
entrez:
2
3
2020
Statut:
ppublish
Résumé
To describe the epidemiological, clinical and microbiological characteristics and mortality of patients with Candida bloodstream infection and systemic autoimmune diseases. We performed a retrospective multicenter study of candidemia in adults with systemic autoimmune diseases between 2010 and 2016. Among 1040 patients with candidemia, 36 (3.5%) had a systemic autoimmune disease. The most common systemic autoimmune disease was rheumatoid arthritis (27.8%). The most common species was Candida albicans (66.7%). Twenty-two (61.1%) patients received a corticosteroid therapy and nine (25%) received an immunosuppressive therapy at the time of candidemia. The mortality rate was 27.8%. Systemic autoimmune diseases are not common in patients with candidemia. The unadjusted mortality rate was comparable to other candidemia studies in the general population.
Identifiants
pubmed: 32113868
pii: S0399-077X(20)30049-4
doi: 10.1016/j.medmal.2020.01.014
pii:
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Immunosuppressive Agents
0
Methotrexate
YL5FZ2Y5U1
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
372-376Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.