Contribution of usage to endoscope working channel damage and bacterial contamination.


Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 20 09 2019
accepted: 04 03 2020
pubmed: 15 3 2020
medline: 10 2 2021
entrez: 15 3 2020
Statut: ppublish

Résumé

Biofilm formation has been shown to be associated with damaged areas of endoscope channels. It was hypothesized that the passage of instruments and brushes through endoscope channels during procedures and cleaning contributes to channel damage, bacterial attachment and biofilm formation. To compare surface roughness and bacterial attachment in used and new endoscope channels in vivo and in vitro. Surface roughness of 10 clinically used (retired) and seven new colonoscope biopsy channels was analysed by a surface profiler. For the in-vitro study, a flexible endoscope biopsy forceps was passed repeatedly through a curved 3.0-mm-diameter Teflon tube 100, 200 and 500 times. Atomic force microscopy was used to determine the degree of inner surface damage. The number of Escherichia coli or Enterococcus faecium attached to the inner surface of the new Teflon tube and the tube with 500 forceps passes in 1 h at 37 The average surface roughness of the used biopsy channels was found to be 1.5 times greater than that of the new biopsy channels (P=0.03). Surface roughness of Teflon tubes with 100, 200 and 500 forceps passes was 1.05-, 1.12- and 3.2-fold (P=0.025) greater than the roughness of the new Teflon tubes, respectively. The number of E. coli and E. faecium attached to Teflon tubes with 500 forceps passes was 2.9-fold (P=0.021) and 4.3-fold (P=0.004) higher compared with the number of E. coli and E. faecium attached to the new Teflon tubes, respectively. An association was found between endoscope usage with damage to the biopsy channel and increased bacterial attachment.

Sections du résumé

BACKGROUND BACKGROUND
Biofilm formation has been shown to be associated with damaged areas of endoscope channels. It was hypothesized that the passage of instruments and brushes through endoscope channels during procedures and cleaning contributes to channel damage, bacterial attachment and biofilm formation.
AIM OBJECTIVE
To compare surface roughness and bacterial attachment in used and new endoscope channels in vivo and in vitro.
METHODS METHODS
Surface roughness of 10 clinically used (retired) and seven new colonoscope biopsy channels was analysed by a surface profiler. For the in-vitro study, a flexible endoscope biopsy forceps was passed repeatedly through a curved 3.0-mm-diameter Teflon tube 100, 200 and 500 times. Atomic force microscopy was used to determine the degree of inner surface damage. The number of Escherichia coli or Enterococcus faecium attached to the inner surface of the new Teflon tube and the tube with 500 forceps passes in 1 h at 37
RESULTS RESULTS
The average surface roughness of the used biopsy channels was found to be 1.5 times greater than that of the new biopsy channels (P=0.03). Surface roughness of Teflon tubes with 100, 200 and 500 forceps passes was 1.05-, 1.12- and 3.2-fold (P=0.025) greater than the roughness of the new Teflon tubes, respectively. The number of E. coli and E. faecium attached to Teflon tubes with 500 forceps passes was 2.9-fold (P=0.021) and 4.3-fold (P=0.004) higher compared with the number of E. coli and E. faecium attached to the new Teflon tubes, respectively.
CONCLUSION CONCLUSIONS
An association was found between endoscope usage with damage to the biopsy channel and increased bacterial attachment.

Identifiants

pubmed: 32169614
pii: S0195-6701(20)30106-7
doi: 10.1016/j.jhin.2020.03.007
pii:
doi:

Substances chimiques

Polytetrafluoroethylene 9002-84-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

176-182

Informations de copyright

Copyright © 2020 The Healthcare Infection Society. All rights reserved.

Auteurs

L C S Santos (LCS)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia; Ribeirao Preto Nursing School, Sao Paulo University, Ribeirao Preto, Sao Paulo, Brazil.

F Parvin (F)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

A Huizer-Pajkos (A)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

J Wang (J)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

D W Inglis (DW)

School of Engineering, Macquarie University, Sydney, Australia.

D Andrade (D)

Ribeirao Preto Nursing School, Sao Paulo University, Ribeirao Preto, Sao Paulo, Brazil.

H Hu (H)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

K Vickery (K)

Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia. Electronic address: karen.vickery@mq.edu.au.

Articles similaires

Biofilms Candida albicans Quorum Sensing Candida glabrata Menthol
Female Biofilms Animals Lactobacillus Mice
Host Specificity Bacteriophages Genomics Algorithms Escherichia coli

Naturally derived 3-aminoquinuclidine salts as new promising therapeutic agents.

Doris Crnčević, Alma Ramić, Andreja Radman Kastelic et al.
1.00
Humans Microbial Sensitivity Tests Anti-Bacterial Agents Biofilms Quinuclidines

Classifications MeSH