An RNA thermoswitch regulates daytime growth in Arabidopsis.
Journal
Nature plants
ISSN: 2055-0278
Titre abrégé: Nat Plants
Pays: England
ID NLM: 101651677
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
05
09
2019
accepted:
10
03
2020
pubmed:
15
4
2020
medline:
10
2
2021
entrez:
15
4
2020
Statut:
ppublish
Résumé
Temperature is a major environmental cue affecting plant growth and development. Plants often experience higher temperatures in the context of a 24 h day-night cycle, with temperatures peaking in the middle of the day. Here, we find that the transcript encoding the bHLH transcription factor PIF7 undergoes a direct increase in translation in response to warmer temperature. Diurnal expression of PIF7 transcript gates this response, allowing PIF7 protein to quickly accumulate in response to warm daytime temperature. Enhanced PIF7 protein levels directly activate the thermomorphogenesis pathway by inducing the transcription of key genes such as the auxin biosynthetic gene YUCCA8, and are necessary for thermomorphogenesis to occur under warm cycling daytime temperatures. The temperature-dependent translational enhancement of PIF7 messenger RNA is mediated by the formation of an RNA hairpin within its 5' untranslated region, which adopts an alternative conformation at higher temperature, leading to increased protein synthesis. We identified similar hairpin sequences that control translation in additional transcripts including WRKY22 and the key heat shock regulator HSFA2, suggesting that this is a conserved mechanism enabling plants to respond and adapt rapidly to high temperatures.
Identifiants
pubmed: 32284544
doi: 10.1038/s41477-020-0633-3
pii: 10.1038/s41477-020-0633-3
pmc: PMC7231574
mid: EMS86331
doi:
Substances chimiques
Arabidopsis Proteins
0
DNA-Binding Proteins
0
PIF7 protein, Arabidopsis
0
RNA, Plant
0
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
522-532Subventions
Organisme : Wellcome Trust
ID : 096082
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 106207
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R011605/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M011747/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 202797/Z/16/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R021821/1
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
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