Extracorporeal Hemadsorption


Journal

Cardiovascular therapeutics
ISSN: 1755-5922
Titre abrégé: Cardiovasc Ther
Pays: England
ID NLM: 101319630

Informations de publication

Date de publication:
2020
Historique:
received: 18 10 2019
accepted: 22 02 2020
entrez: 16 4 2020
pubmed: 16 4 2020
medline: 7 7 2020
Statut: epublish

Résumé

Extracorporeal hemadsorption may reduce inflammatory reaction in cardiopulmonary bypass (CPB) surgery. Glucocorticoids have been used during open-heart surgery for alleviation of systemic inflammation after CPB. We compared intraoperative hemadsorption and methylprednisolone, with usual care, during complex cardiac surgery on CPB, for inflammatory responses, hemodynamics, and perioperative course. Seventy-six patients with prolonged CPB were recruited and randomized, with 60 included in final analysis. Allocation was into three groups: Methylprednisolone (

Identifiants

pubmed: 32292492
doi: 10.1155/2020/7834173
pmc: PMC7149340
doi:

Substances chimiques

Anti-Inflammatory Agents 0
Biomarkers 0
Cytokines 0
Glucocorticoids 0
Inflammation Mediators 0
Methylprednisolone X4W7ZR7023

Banques de données

ClinicalTrials.gov
['NCT02666703']

Types de publication

Comparative Study Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

7834173

Informations de copyright

Copyright © 2020 Gordana Taleska Stupica et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this article.

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Auteurs

Gordana Taleska Stupica (G)

Clinical Department of Anaesthesiology and Perioperative Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Maja Sostaric (M)

Clinical Department of Anaesthesiology and Perioperative Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia.
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia.

Marija Bozhinovska (M)

Clinical Department of Anaesthesiology and Perioperative Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Lea Rupert (L)

Clinical Department of Anaesthesiology and Perioperative Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Zoran Bosnic (Z)

University of Ljubljana, Faculty of Computer and Information Science, Ljubljana, Slovenia.

Ales Jerin (A)

Institute of Clinical Chemistry and Biochemistry, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Alojz Ihan (A)

University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia.

Tomislav Klokocovnik (T)

Clinical Department of Cardio-Vascular Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Matej Podbregar (M)

Clinical Department of Anaesthesiology and Perioperative Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia.
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia.
Department of Internal Intensive Medicine, General and Teaching Hospital, Celje, Slovenia.

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