3-Hydroxybutyrate Is Active Compound in Flax That Upregulates Genes Involved in DNA Methylation.
3-Hydroxybutyric Acid
/ metabolism
DNA Methylation
Epigenesis, Genetic
Flax
/ drug effects
Gas Chromatography-Mass Spectrometry
Gene Expression Regulation, Plant
/ drug effects
Genes, Plant
Metabolic Networks and Pathways
Plants, Genetically Modified
Propanols
/ metabolism
RNA, Messenger
Spectroscopy, Fourier Transform Infrared
3-hydroxybutyrate
DNA methylation
flax
lignin metabolism
methyltransferase 3
β-ketothiolase
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
21 Apr 2020
21 Apr 2020
Historique:
received:
26
03
2020
revised:
14
04
2020
accepted:
17
04
2020
entrez:
25
4
2020
pubmed:
25
4
2020
medline:
26
1
2021
Statut:
epublish
Résumé
In mammalian cells, 3-hydroxybutyrate (3-HB) is not only an intermediate metabolite during the oxidation of fatty acids, but also an important signaling molecule. On the other hand, the information about the metabolism or function of this compound in plants is scarce. In our study, we show for the first time that this compound naturally occurs in flax. The expression of bacterial
Identifiants
pubmed: 32326145
pii: ijms21082887
doi: 10.3390/ijms21082887
pmc: PMC7215830
pii:
doi:
Substances chimiques
Propanols
0
RNA, Messenger
0
1-phenylpropanol
0F897O3O4M
3-Hydroxybutyric Acid
TZP1275679
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Narodowe Centrum Nauki
ID : 2017/27/N/NZ9/00387
Références
Mol Cell. 2006 Oct 6;24(1):1-11
pubmed: 17018288
Annu Rev Microbiol. 2002;56:403-32
pubmed: 12213937
Chembiochem. 2001 Oct 1;2(10):784-6
pubmed: 11948863
Science. 2009 May 22;324(5930):1076-80
pubmed: 19461003
J Plant Physiol. 2016 Aug 20;201:9-16
pubmed: 27372278
Curr Opin Plant Biol. 2017 Apr;36:103-110
pubmed: 28258985
Trends Plant Sci. 2007 Jan;12(1):29-36
pubmed: 17161643
Neuroscience. 2007 Mar 2;145(1):256-64
pubmed: 17240074
J Bacteriol. 2013 Jul;195(14):3213-23
pubmed: 23667237
Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2078-2083
pubmed: 28130550
Nature. 2015 Jan 29;517(7536):571-5
pubmed: 25533953
Nat Rev Mol Cell Biol. 2018 Aug;19(8):489-506
pubmed: 29784956
Mol Plant. 2015 Jan;8(1):83-97
pubmed: 25578274
Biotechnol Adv. 2018 May - Jun;36(3):856-870
pubmed: 29248684
Science. 2013 Jan 11;339(6116):211-4
pubmed: 23223453
J Cereb Blood Flow Metab. 2015 Nov;35(11):1783-9
pubmed: 26058697
J Bacteriol. 2007 Nov;189(22):8250-6
pubmed: 17720797
Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jul 15;73(2):286-94
pubmed: 19328737
J Neurochem. 2016 Dec;139(5):769-781
pubmed: 27739595
J Biotechnol. 2004 Jan 8;107(1):41-54
pubmed: 14687970
Mol Cell. 2006 Jul 21;23(2):207-17
pubmed: 16857587
J Bacteriol. 2003 Jan;185(2):399-404
pubmed: 12511484
Nat Genet. 1999 May;22(1):98-101
pubmed: 10319871
PLoS One. 2018 Feb 28;13(2):e0190556
pubmed: 29489818
Cell. 2012 Sep 28;151(1):167-80
pubmed: 23021223
Gene Expr. 2000;9(1-2):63-75
pubmed: 11097425
Molecules. 2014 Oct 10;19(10):16240-65
pubmed: 25310150
Cell. 2013 Mar 28;153(1):193-205
pubmed: 23540698
Front Plant Sci. 2017 May 15;8:755
pubmed: 28555142
Front Plant Sci. 2016 Jun 24;7:894
pubmed: 27446124
Nature. 2000 Feb 17;403(6771):795-800
pubmed: 10693811
J Bacteriol. 1973 Nov;116(2):989-93
pubmed: 4583258
Elife. 2016 Jun 02;5:
pubmed: 27253067
J Biol Chem. 2016 Mar 18;291(12):6471-82
pubmed: 26792862
Appl Environ Microbiol. 2019 Mar 6;85(6):
pubmed: 30610076
PLoS One. 2009 Jun 16;4(6):e5932
pubmed: 19529764
Aging (Albany NY). 2014 Aug;6(8):621-44
pubmed: 25127866
Science. 2009 Mar 20;323(5921):1600-4
pubmed: 19179494
Microbiol Rev. 1990 Dec;54(4):450-72
pubmed: 2087222
Microbiology. 2007 Feb;153(Pt 2):388-398
pubmed: 17259610
Mol Breed. 2014;34(4):1917-1932
pubmed: 25506258
Plant Physiol. 1984 Aug;75(4):1158-62
pubmed: 16663750
Appl Environ Microbiol. 2008 Feb;74(4):1058-63
pubmed: 18156336