Production of Antitubercular Depsipeptides via Biosynthetic Engineering of Cinnamoyl Units.

Antitubercular Agents / chemistry Biosynthetic Pathways Crystallography, X-Ray Depsipeptides / chemistry Microbial Sensitivity Tests Molecular Structure Mycobacterium tuberculosis / chemistry Streptomyces / chemistry

Journal

Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882

Informations de publication

Date de publication:
22 05 2020
Historique:
pubmed: 28 4 2020
medline: 30 7 2021
entrez: 28 4 2020
Statut: ppublish

Résumé

Two new cyclodecapeptides, atratumycins B (

Identifiants

DOI: 10.1021/acs.jnatprod.0c00194 PMID: 32338895
pubmed: 32338895
doi: 10.1021/acs.jnatprod.0c00194
doi:

Substances chimiques

Antitubercular Agents 0
Depsipeptides 0
atratumycin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1666-1673

Auteurs

Zhijie Yang (Z)

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, People's Republic of China.
College of Oceanology, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.

Changli Sun (C)

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, People's Republic of China.

Zhiyong Liu (Z)

Tuberculosis Research Laboratory, State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, People's Republic of China.
Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Guangzhou 510530, People's Republic of China.

Qing Liu (Q)

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, People's Republic of China.

Tianyu Zhang (T)

College of Oceanology, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Tuberculosis Research Laboratory, State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, People's Republic of China.
Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Guangzhou 510530, People's Republic of China.
ORCID: 0000-0001-5647-6014

Jianhua Ju (J)

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, People's Republic of China.
College of Oceanology, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
ORCID: 0000-0001-7712-8027

Junying Ma (J)

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, People's Republic of China.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Antituberculeux › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Métabolisme › Voies et réseaux métaboliques › Voies de biosynthèse › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides cycliques › Depsipeptides › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › Production of Antitubercular Depsipeptides via...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets sporulés à Gram positif › Streptomycetaceae › Streptomyces › Production of Antitubercular Depsipeptides via...