Dosimetric performance of a multipoint plastic scintillator dosimeter as a tool for real-time source tracking in high dose rate

HDR brachytherapy in vivo dosimetry multipoint plastic scintillator detector plastic scintillator source tracking

Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 25 10 2019
revised: 03 04 2020
accepted: 11 05 2020
pubmed: 23 5 2020
medline: 15 5 2021
entrez: 23 5 2020
Statut: ppublish

Résumé

This study aims to present the performance of a multipoint plastic scintillation detector (mPSD) as a tool for real-time dose measurements (covering three orders of magnitude in dose rate), source-position triangulation, and dwell time assessment in high dose rate (HDR) brachytherapy. A previously characterized and optimized three-point sensor system was used for HDR brachytherapy measurements. The detector was composed of three scintillators: BCF60, BCF12, and BCF10. Scintillation light was transmitted through a single 1-mm-diameter clear optical fiber and read by a compact assembly of photomultiplier tubes (PMTs). Each component was numerically optimized to allow for signal deconvolution using a multispectral approach, taking care of the Cerenkov stem effect as well as extracting the dose from each scintillator. The PMTs were read simultaneously using a data acquisition board at a rate of 100 KHz and controlled with in-house software based on Python. An As expected, the positioning uncertainty dominated close to the source, whereas the measurement uncertainty dominated at larger distances. A maximum measurement uncertainty of 17 % was observed for the BCF60 scintillator at 10 cm from the source. Based on the uncertainty chain, the best compromises between positioning and measurement uncertainties were reached at 17.2, 17.4, and 17.5 mm for the BCF10, BCF12, and BCF60 scintillators, respectively, which also corresponded to the recommended optimal distances to the source for calibration purposes. The detector further exhibited no angular dependence. All dose values were found to be within 2% of the dose value at Real-time HDR brachytherapy measurements were performed with an optimized mPSD system. The performance of the system demonstrated that it could be used for simultaneous, in vivo, real-time reporting of dose, dwell time, and source position during HDR brachytherapy.

Identifiants

pubmed: 32443175
doi: 10.1002/mp.14246
doi:

Substances chimiques

Plastics 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4477-4490

Subventions

Organisme : National Sciences and Engineering Research Council of Canada
Organisme : NSERC-Elekta Industrial Research Chair
ID : 484144-15
Organisme : NSERC-Elekta Industrial Research Chair
ID : RGPIN-2019-05038
Organisme : Canadian Foundation for Innovation
Organisme : JR Evans Leader Funds
ID : 35633
Organisme : Fonds de Recherche du Quebec - Nature et Technologies
Organisme : CREATE Medical Physics Research Training Network
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : 432290

Informations de copyright

© 2020 American Association of Physicists in Medicine.

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Auteurs

Haydee M Linares Rosales (HM)

Département de physique, de génie physique et d'optique et Centre de recherche sur le cancer, Université Laval, Québec, Canada.
Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, CHU de Québec - Université Laval, Québec, QC, Canada.

Louis Archambault (L)

Département de physique, de génie physique et d'optique et Centre de recherche sur le cancer, Université Laval, Québec, Canada.
Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, CHU de Québec - Université Laval, Québec, QC, Canada.

Sam Beddar (S)

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.

Luc Beaulieu (L)

Département de physique, de génie physique et d'optique et Centre de recherche sur le cancer, Université Laval, Québec, Canada.
Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, CHU de Québec - Université Laval, Québec, QC, Canada.

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