A novel pectin from Polygala tenuifolia blocks Aβ

Amyloid beta-Peptides / metabolism Cell Line Gene Expression Regulation, Enzymologic / drug effects Hydrolysis Insulysin / genetics Magnetic Resonance Spectroscopy Molecular Weight Neprilysin / genetics Pectins / chemistry Polygala / chemistry Protein Aggregates / drug effects Proteolysis / drug effects Spectroscopy, Fourier Transform Infrared
Aβ(42). Alzheimer's disease Pectin Polygala tenuifolia Polysaccharide

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
15 Oct 2020
Historique:
received: 03 03 2020
revised: 11 05 2020
accepted: 25 05 2020
pubmed: 31 5 2020
medline: 27 3 2021
entrez: 31 5 2020
Statut: ppublish

Résumé

More and more evidences show that pectin polysaccharide may have impact on Aβ

Identifiants

DOI: 10.1016/j.ijbiomac.2020.05.212 PMID: 32473218
pubmed: 32473218
pii: S0141-8130(20)33375-4
doi: 10.1016/j.ijbiomac.2020.05.212
pii:
doi:

Substances chimiques

Amyloid beta-Peptides 0
Protein Aggregates 0
Pectins 89NA02M4RX
Neprilysin EC 3.4.24.11
Insulysin EC 3.4.24.56

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

35-43

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Hui Zeng (H)

Glycochemistry and Glycobiology Lab, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China.

Piaopiao Li (P)

School of Basic Medicine, Nanchang University; Nanchang 330006, PR China; Glycochemistry and Glycobiology Lab, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, PR China.

Lishuang Zhou (L)

Glycochemistry and Glycobiology Lab, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China.

Kan Ding (K)

Glycochemistry and Glycobiology Lab, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China. Electronic address: dingkan@simm.ac.cn.

Articles similaires

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions.

Ting-Wen Chen, Hsiao-Wei Liao, Michelle Noble et al.
1.00
Humans Endoribonucleases RNA, Messenger RNA Caps Gene Expression Regulation

Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells.

Rachel B Gilmore, Dea Gorka, Christopher E Stoddard et al.
1.00
Prader-Willi Syndrome Humans Angelman Syndrome CRISPR-Cas Systems Human Embryonic Stem Cells

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Muhammad Atif, Humaira Zafar, Atia-Tul- Wahab et al.
1.00
Fucosyltransferases Drug Repositioning Molecular Docking Simulation Molecular Dynamics Simulation Humans

Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes codant pour des enzymes › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Phénomènes chimiques › Hydrolyse › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Metalloproteases › Metalloendopeptidases › Insulinase › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Phénomènes chimiques › Masse moléculaire › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Néprilysine › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Préparations à base de plantes › Pectine › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Polygalaceae › Polygala › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Structures macromoléculaires › Agrégats de protéines › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Métabolisme › Protéolyse › A novel pectin from Polygala tenuifolia blocks Aβ
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrophotométrie › Spectrophotométrie IR › Spectroscopie infrarouge à transformée de Fourier › A novel pectin from Polygala tenuifolia blocks Aβ