Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways.
Acetylcholine
/ pharmacology
Animals
Anions
/ metabolism
Atropine
/ pharmacology
Cholinergic Agonists
/ pharmacology
Enterocytes
/ drug effects
Hexamethonium
/ pharmacology
Humans
Intestinal Mucosa
/ drug effects
Intestines
/ drug effects
Mice
Muscarinic Agonists
/ pharmacology
Non-Neuronal Cholinergic System
/ drug effects
Receptors, Muscarinic
/ genetics
Receptors, Nicotinic
/ genetics
anion secretion
cholinergic
enteroids
monolayers
nicotinic
Journal
American journal of physiology. Cell physiology
ISSN: 1522-1563
Titre abrégé: Am J Physiol Cell Physiol
Pays: United States
ID NLM: 100901225
Informations de publication
Date de publication:
01 08 2020
01 08 2020
Historique:
pubmed:
20
6
2020
medline:
23
10
2020
entrez:
20
6
2020
Statut:
ppublish
Résumé
Acetylcholine induces robust electrogenic anion secretion in mammalian intestine and it has long been hypothesized that it mediates the epithelial response through the M
Identifiants
pubmed: 32551856
doi: 10.1152/ajpcell.00179.2020
pmc: PMC7500216
doi:
Substances chimiques
Anions
0
Cholinergic Agonists
0
Muscarinic Agonists
0
Receptors, Muscarinic
0
Receptors, Nicotinic
0
Hexamethonium
3C9PSP36Z2
Atropine
7C0697DR9I
Acetylcholine
N9YNS0M02X
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
C321-C330Subventions
Organisme : NIDDK NIH HHS
ID : R24 DK099803
Pays : United States
Organisme : NIH NIDDK
ID : P30DK089502
Pays : International
Organisme : NIH HHS
ID : 1S10OD025244
Pays : United States
Organisme : NIDDK NIH HHS
ID : K01 DK106323
Pays : United States
Organisme : NIH HHS
ID : S10 OD025244
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK116352
Pays : United States
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