Restriction site-associated DNA sequencing (RAD-seq) analysis in Pacific oyster Crassostrea gigas based on observation of individual sex changes.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
18 06 2020
Historique:
received: 14 01 2020
accepted: 03 04 2020
entrez: 20 6 2020
pubmed: 20 6 2020
medline: 15 12 2020
Statut: epublish

Résumé

The diverse modes of sexual reproduction in Bivalvia make it an excellent clade to understand the evolution of sex and sex determination. The cosmopolitan Pacific oyster Crassostrea gigas is an ideal model for bivalve sex determination studies because of its complicated sexuality, including dioecy, sex change and rare hermaphroditism. A major barrier to C. gigas sex determination study has been the lack of information on the type of sex determination. To identify its sex-determining system, sex observation by following the same individual in two consecutive years was conducted on 760 oysters from distinct populations. Stable sexuality and sex reversal in both directions were observed, which provides a case against the protandry of C. gigas. Restriction site-associated DNA sequencing (RAD-seq) based on 26 samples with unchanged and converted sexualities was carried out for identifying sex-linked marker. One SNP Cgsl-40 was proved to be sex-related, but sex-biased heterozygosity varied between populations for RAD-seq and validation, showing no evidence for sex chromosomes or single-locus models for C. gigas primary sex determination. Information obtained in our study provides novel insight into sex determination mechanism in C. gigas.

Identifiants

pubmed: 32555506
doi: 10.1038/s41598-020-67007-4
pii: 10.1038/s41598-020-67007-4
pmc: PMC7303127
doi:

Substances chimiques

Shellfish Proteins 0
RNA 63231-63-0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9873

Références

Piferrer, F. Epigenetics of sex determination and gonadogenesis. Dev. Dyn. 242, 360–70 (2013).
doi: 10.1002/dvdy.23924 pubmed: 23335256
Manolakou, P., Lavranos, G. & Angelopoulou, R. Molecular patterns of sex determination in the animal kingdom: a comparative study of the biology of reproduction. Reprod. Biol. Endocrinol. 4, 59 (2006).
pmcid: 1660543 doi: 10.1186/1477-7827-4-59 pubmed: 17101057
Baroiller, J. F., D’Cotta, H., Bezault, E., Wessels, S. & Hoerstgen-Schwark, G. Tilapia sex determination: where temperature and genetics meet. Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol. 153, 30–8 (2009).
doi: 10.1016/j.cbpa.2008.11.018
Wilson, M. A. & Makova, K. D. Genomic analyses of sex chromosome evolution. Annu. Rev. Genomics Hum. Genet. 10, 333–54 (2009).
doi: 10.1146/annurev-genom-082908-150105 pubmed: 19630566
Liew, W. C. et al. Polygenic sex determination system in zebrafish. PloS One 7, e34397 (2012).
pmcid: 3323597 doi: 10.1371/journal.pone.0034397 pubmed: 22506019
Bull, J., Vogt, R. C. & Bulmer, M. Heritability of sex ratio in turtles with environmental sex determination. Evolution 36, 333–41 (1982).
doi: 10.1111/j.1558-5646.1982.tb05049.x pubmed: 28563174
Bateman, A. W. & Anholt, B. R. Maintenance of polygenic sex determination in a fluctuating environment: an individual-based model. J. Evol. Biol. 30, 915–25 (2017).
doi: 10.1111/jeb.13054 pubmed: 28187242
Modi, W. S. & Crews, D. Sex chromosomes and sex determination in reptiles: Commentary. Curr. Opin. Genet. Dev. 15, 660–5 (2005).
doi: 10.1016/j.gde.2005.09.009 pubmed: 16214335
Grossen, C., Neuenschwander, S. & Perrin, N. Temperature-dependent turnovers in sex-determination mechanisms: a quantitative model. Evolution 65, 64–78 (2011).
doi: 10.1111/j.1558-5646.2010.01098.x pubmed: 20722730
Santerre, C. et al. Oyster sex determination is influenced by temperature—first clues in spat during first gonadic differentiation and gametogenesis. Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol. 165, 61–9 (2013).
doi: 10.1016/j.cbpa.2013.02.007
Liew, W. C. & Orban, L. Zebrafish sex: a complicated affair. Briefings Funct. Genomics 13, 172–87 (2014).
doi: 10.1093/bfgp/elt041
Palaiokostas, C. et al. A new SNP-based vision of the genetics of sex determination in European sea bass (Dicentrarchus labrax). Genet., Sel., Evol. 47, 68 (2015).
doi: 10.1186/s12711-015-0148-y
Coe, W. R. Sexual differentiation in mollusks. I. Pelecypods. Q. Rev. Biol. 18, 154–64 (1943).
doi: 10.1086/394673
Guo, X., Hedgecock, D., Hershberger, W. K., Cooper, K. & Allen, S. K. Jr. Genetic determinants of protandric sex in the Pacific oyster, Crassostrea gigas Thunberg. Evolution 52, 394–402 (1998).
doi: 10.1111/j.1558-5646.1998.tb01640.x pubmed: 28568342
Breton, S., Capt, C., Guerra, D., & Stewart, D. Sex-determining mechanisms in bivalves in Transitions Between Sexual Systems (ed. Leonard, J.L.) 165-192 (Springer, 2018).
Guo, X. & Allen, S. K. Sex determination and polyploid gigantism in the dwarf surfclam (Mulinia lateralis Say). Genetics 138(4), 1199–1206 (1994).
pmcid: 1206258 pubmed: 7896101
Coe, W. R. Sexual phases in the American oyster (Ostrea Virginica). Biol. Bull. 63, 419–41 (1932).
doi: 10.2307/1537344
Chávez-Villalba, J. et al. Determination of gender in the pearl oyster Pinctada margaritifera. J. Shellfish Res. 30, 231–40 (2011).
doi: 10.2983/035.030.0206
Coe, W. R. Environment and sex in the oviparous oyster Ostrea virginica. Biol. Bull. 71, 353–359 (1936).
doi: 10.2307/1537440
Haley, L. E. Sex determination in the American oyster. J. Hered. 68, 114–116 (1977).
doi: 10.1093/oxfordjournals.jhered.a108784
Haley, L. E. Genetics of sex determination in the American oyster. Proc Natl Shellfishries Association 69, 54–57 (1979).
Park, J. J. et al. Sex ratio and sex reversal in two-year-old class of oyster, Crassostrea gigas (Bivalvia: Ostreidae). Dev. Reprod. 16, 385–8 (2012).
pmcid: 4282249 doi: 10.12717/DR.2012.16.4.385 pubmed: 25949114
Yasuoka, N. & Yusa, Y. Effects of size and gregariousness on individual sex in a natural population of the Pacific oyster Crassostrea gigas. J. Mollus. Stud. 82, 485–91 (2016).
doi: 10.1093/mollus/eyw020
Lango-Reynoso, F., Chavez-Villaba, J. & Le Pennec, M. Reproductive patterns of the Pacific oyster Crassostrea gigas in France. Invertebr. Reprod. Dev. 49, 41–50 (2006).
doi: 10.1080/07924259.2006.9652192
Hedrick, P. W. & Hedgecock, D. Sex determination: genetic models for oysters. J. Hered. 101, 602–11 (2010).
doi: 10.1093/jhered/esq065 pubmed: 20525766
Li, L. & Guo, X. AFLP-based genetic linkage maps of the Pacific oyster Crassostrea gigas Thunberg. Mar. Biotechnol. 6, 26–36 (2004).
doi: 10.1007/s10126-003-0001-0 pubmed: 14564534
Zhang, N., Xu, F. & Guo, X. Genomic analysis of the Pacific oyster (Crassostrea gigas) reveals possible conservation of vertebrate sex determination in a mollusc. G3: Genes, Genomes, Genet. 4, 2207–17 (2014).
doi: 10.1534/g3.114.013904
Yue, C., Li, Q. & Yu, H. Gonad transcriptome analysis of the Pacific oyster Crassostrea gigas identifies potential genes regulating the sex determination and differentiation process. Mar. Biotechnol. 20, 206–19 (2018).
doi: 10.1007/s10126-018-9798-4 pubmed: 29516375
Santerre, C., Sourdaine, P. & Martinez, A.-S. Expression of a natural antisense transcript of Cg-Foxl2 during the gonadic differentiation of the oyster Crassostrea gigas: first demonstration in the gonads of a lophotrochozoa species. Sex. Dev. 6, 210–21 (2012).
doi: 10.1159/000338085 pubmed: 22572405
Brelsford, A., Lavanchy, G., Sermier, R., Rausch, A. & Perrin, N. Identifying homomorphic sex chromosomes from wild-caught adults with limited genomic resources. Mol. Ecol. Resour. 17, 752–9 (2017).
doi: 10.1111/1755-0998.12624 pubmed: 27790846
Gamble, T. & Zarkower, D. Identification of sex-specific molecular markers using restriction site-associated DNA sequencing. Mol. Ecol. Resour. 14, 902–13 (2014).
pubmed: 24506574
Gamble, T. et al. Restriction site-associated DNA sequencing (RAD-seq) reveals an extraordinary number of transitions among gecko sex-determining systems. Mol. Biol. Evol. 32, 1296–309 (2015).
doi: 10.1093/molbev/msv023 pubmed: 25657328
Liu, H. et al. Sex-specific markers developed by next-generation sequencing confirmed an XX/XY sex determination system in bighead carp (Hypophthalmichehys nobilis) and silver carp (Hypophthalmichthys molitrix). DNA Res. 25, 257–64 (2018).
pmcid: 6014435 doi: 10.1093/dnares/dsx054
Broquard, C., Martinez, A. S., Maurouard, E., Lamy, J. B. & Dégremont, L. Sex determination in the oyster Crassostrea gigas-A large longitudinal study of population sex ratios and individual sex changes. Aquaculture 515, 734555 (2020).
doi: 10.1016/j.aquaculture.2019.734555
Namba, K. et al. Persistent relaxation of the adductor muscle of oyster Crassostrea gigas induced by magnesium ion. Fish. Sci. 61, 241–4 (1995).
doi: 10.2331/fishsci.61.241
Leitão, A., Chaves, R., Santos, S., Guedes-Pinto, H. & Boudry, P. Interspecific hybridization in oysters: restriction enzyme digestion chromosome banding confirms Crassostrea angulata×Crassostrea gigas F1 hybrids. J. Exp. Mar. Biol. Ecol. 343, 253–60 (2007).
doi: 10.1016/j.jembe.2006.12.007
Magerhans, A., Müller-Belecke, A. & Hörstgen-Schwark, G. Effect of rearing temperatures post hatching on sex ratios of rainbow trout (Oncorhynchus mykiss) populations. Aquaculture 294, 25–9 (2009).
doi: 10.1016/j.aquaculture.2009.05.001
Bradley, K. M. et al. An SNP-based linkage map for zebrafish reveals sex determination loci. G3: Genes, Genomes, Genet. 1, 3–9 (2011).
doi: 10.1534/g3.111.000190
Howe, K. et al. The zebrafish reference genome sequence and its relationship to the human genome. Nature 496, 498–503 (2013).
pmcid: 3703927 doi: 10.1038/nature12111 pubmed: 23594743
Nagabhushana, A. & Mishra, R. K. Finding clues to the riddle of sex determination in zebrafish. J. Biosci. 41, 145–55 (2016).
doi: 10.1007/s12038-016-9593-1 pubmed: 26949096
Kosswig, C. Polygenic sex determination. Cell. Mol. Life Sci. 20, 190–9 (1964).
doi: 10.1007/BF02135395
Bull, J. Sex determining mechanisms: an evolutionary perspective. Experientia 41, 1285–96 (1985).
doi: 10.1007/BF01952071 pubmed: 3899710

Auteurs

Chenyang Yue (C)

Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, China.

Qi Li (Q)

Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, China. qili66@ouc.edu.cn.
Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China. qili66@ouc.edu.cn.

Hong Yu (H)

Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, China.

Shikai Liu (S)

Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, China.

Lingfeng Kong (L)

Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, China.

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