SpeS: A Novel Superantigen and Its Potential as a Vaccine Adjuvant against Strangles.
Adjuvants, Immunologic
/ chemistry
Antigen Presentation
/ immunology
Bacterial Proteins
/ immunology
Exotoxins
/ immunology
Histocompatibility Antigens Class II
/ immunology
Humans
Membrane Proteins
/ immunology
Meningitis
Phylogeny
Receptors, Antigen, T-Cell
/ metabolism
Streptococcal Infections
/ immunology
Streptococcus equi
/ immunology
Superantigens
/ immunology
Vaccines
/ administration & dosage
Streptococcus equi
Streptococcus zooepidemicus
adjuvant
horse
immune response
strangles
superantigen
vaccine
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
23 Jun 2020
23 Jun 2020
Historique:
received:
22
05
2020
revised:
19
06
2020
accepted:
19
06
2020
entrez:
27
6
2020
pubmed:
27
6
2020
medline:
23
3
2021
Statut:
epublish
Résumé
Bacterial superantigens (sAgs) are powerful activators of the immune response that trigger unspecific T cell responses accompanied by the release of proinflammatory cytokines.
Identifiants
pubmed: 32586031
pii: ijms21124467
doi: 10.3390/ijms21124467
pmc: PMC7352279
pii:
doi:
Substances chimiques
Adjuvants, Immunologic
0
Bacterial Proteins
0
Exotoxins
0
Histocompatibility Antigens Class II
0
Membrane Proteins
0
Receptors, Antigen, T-Cell
0
SpeA protein, Streptococcus pyogenes
0
Superantigens
0
Vaccines
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P002757/1
Pays : United Kingdom
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