Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs.
Candida albicans
aneuploidy
copy number variation
dicentric chromosomes
drug resistance
drug tolerance
genetics
genomics
infectious disease
microbiology
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
20 07 2020
20 07 2020
Historique:
received:
28
04
2020
accepted:
09
07
2020
entrez:
21
7
2020
pubmed:
21
7
2020
medline:
17
2
2021
Statut:
epublish
Résumé
Previously, we identified long repeat sequences that are frequently associated with genome rearrangements, including copy number variation (CNV), in many diverse isolates of the human fungal pathogen
Identifiants
pubmed: 32687060
doi: 10.7554/eLife.58349
pii: 58349
pmc: PMC7371428
doi:
pii:
Substances chimiques
Antifungal Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : R01 AI143689
Pays : United States
Informations de copyright
© 2020, Todd and Selmecki.
Déclaration de conflit d'intérêts
RT, AS No competing interests declared
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