Bioinformatics Resources for RNA Editing.

Animals Computational Biology / methods High-Throughput Nucleotide Sequencing Humans Practice Guidelines as Topic RNA Editing / physiology Sequence Analysis, RNA Transcriptome
A-to-I editing Bioinformatics Deep sequencing RNA editing RNA-Seq Transcriptome

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2021
Historique:
entrez: 31 7 2020
pubmed: 31 7 2020
medline: 27 2 2021
Statut: ppublish

Résumé

RNA editing is a widespread co/posttranscriptional mechanism affecting primary RNAs by specific nucleotide modifications, which plays relevant roles in molecular processes including regulation of gene expression and/or processing of noncoding RNAs (ncRNAs). In recent years, the detection of editing sites has been greatly improved through the availability of high-throughput RNA sequencing technologies. Several pipelines, employing various read mappers and variant callers with a wide range of adjustable parameters, are currently available for the detection of RNA editing events. Hereafter, we describe some of the most recent and popular tools and provide guidelines for the detection of RNA editing in massive transcriptome data.

Identifiants

DOI: 10.1007/978-1-0716-0787-9_11 PMID: 32729081
pubmed: 32729081
doi: 10.1007/978-1-0716-0787-9_11
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

177-191

Auteurs

Maria Angela Diroma (MA)

Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Bari, Italy.

Loredana Ciaccia (L)

Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari "A. Moro", Bari, Italy.

Graziano Pesole (G)

Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Bari, Italy.
Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari "A. Moro", Bari, Italy.

Ernesto Picardi (E)

Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Bari, Italy. ernesto.picardi@uniba.it.
Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari "A. Moro", Bari, Italy. ernesto.picardi@uniba.it.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Séquençage nucléotidique à haut débit › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Assurance de la qualité des soins de santé › Recommandations comme sujet › Guides de bonnes pratiques cliniques comme sujet › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Maturation post-transcriptionnelle des ARN › Édition des ARN › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ARN › Bioinformatics Resources for RNA Editing.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Transcriptome › Bioinformatics Resources for RNA Editing.