Parametric optimization and kinetic study of l-lactic acid production by homologous batch fermentation of Lactobacillus pentosus cells.


Journal

Biotechnology and applied biochemistry
ISSN: 1470-8744
Titre abrégé: Biotechnol Appl Biochem
Pays: United States
ID NLM: 8609465

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 21 02 2020
accepted: 25 06 2020
pubmed: 2 8 2020
medline: 30 9 2021
entrez: 2 8 2020
Statut: ppublish

Résumé

Parametric optimization always plays important roles in bioengineering systems to obtain a high product yield under the proper conditions. The parametric conditions of lactic acid production by homologous batch fermentation of Lactobacillus pentosus cells was optimized by the Box-Behnken design. The highest l-lactic acid yield was obtained as 0.836 ± 0.003 g/g glucose with the productivity of 0.906 ± 0.003 g/(L × H) under the optimum conditions of 34.7 °C, pH 6.2, 148 rpm agitation speed, and 9.3 g/L nitrogen source concentration determined by quadratic response surface with high accuracy. The adequate kinetic models of cell growth rate, lactic production rate, and glucose consumption rate were also established to describe the fermentation behavior of L. pentosus cells with the correlation coefficients of 09985, 0.9990, and 0.9989, respectively.

Identifiants

pubmed: 32738151
doi: 10.1002/bab.1994
doi:

Substances chimiques

Lactic Acid 33X04XA5AT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

809-822

Informations de copyright

© 2020 International Union of Biochemistry and Molecular Biology, Inc.

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Auteurs

Jianfei Wang (J)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Jiaqi Huang (J)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.
The Center for Biotechnology & Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute, Troy, USA.

Shaoming Jiang (S)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Jing Zhang (J)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Quanquan Zhang (Q)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Yuchen Ning (Y)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Mudannan Fang (M)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

Shijie Liu (S)

Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, Syracuse, USA.

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