Role of nutraceutical starch and proanthocyanidins of pigmented rice in regulating hyperglycemia: Enzyme inhibition, enhanced glucose uptake and hepatic glucose homeostasis using in vitro model.
Biological Transport
/ drug effects
Dietary Supplements
/ analysis
Glucose
/ metabolism
Glycoside Hydrolase Inhibitors
/ pharmacology
Homeostasis
/ drug effects
Hyperglycemia
/ metabolism
Liver
/ drug effects
Oryza
/ chemistry
Phenol
/ analysis
Proanthocyanidins
/ analysis
Starch
/ analysis
alpha-Amylases
/ antagonists & inhibitors
4-Nitrophenyl α-D glucopyranoside (PubChem CID92969)
Acarbose (PubChem CID41774)
Anti-hyperglycemic
Black rice
C(14)glucose (PubChem CID6451569)
Dinitrosalicyclic acid (PubChem CID11873)
Folin’s reagent (PubChem CID10636)
Gallic acid (PubChem CID370)
Gentamycin (PubChem CID3467)
Glucose homeostasis
Glucose uptake
Hepatocyte
Penicillin (PubChem CID5904)
Pigmented rice
Proanthocyanidins
Propidium iodide (PubChem CID104981)
Red rice
Rutin (PubChem CID45479757)
Serum albumin (PubChem CID16132389)
Starch soluble (PubChem CID 134690613)
Streptomycin (PubChem CID19649)
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
15 Jan 2021
15 Jan 2021
Historique:
received:
05
03
2020
revised:
14
05
2020
accepted:
04
07
2020
pubmed:
3
8
2020
medline:
30
10
2020
entrez:
3
8
2020
Statut:
ppublish
Résumé
Dysregulation of glucose homeostasis result in hyperglycemia and pigmented rice, unique combination of high quality starch and phenolics has the potential in regulating it. In this study, pigmented rice was characterized in terms of nutraceutical starch (NS) and phenolic content. Further the effect of rice phenolics on carbolytic enzyme inhibition, glucose uptake, hepatic glucose homeostasis and anti-glycation ability was analyzed in vitro. The most relevant effect on enzyme inhibition (α-amylase: IC
Identifiants
pubmed: 32739823
pii: S0308-8146(20)31367-4
doi: 10.1016/j.foodchem.2020.127505
pii:
doi:
Substances chimiques
Glycoside Hydrolase Inhibitors
0
Proanthocyanidins
0
Phenol
339NCG44TV
Starch
9005-25-8
alpha-Amylases
EC 3.2.1.1
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
127505Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.