Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome.
ALS
Neurodegenerative
Neurodevelopmental
Repeats
Ubiquitin
Journal
Neurobiology of aging
ISSN: 1558-1497
Titre abrégé: Neurobiol Aging
Pays: United States
ID NLM: 8100437
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
04
01
2020
revised:
22
07
2020
accepted:
25
07
2020
pubmed:
28
8
2020
medline:
2
9
2021
entrez:
27
8
2020
Statut:
ppublish
Résumé
More than 40 human diseases, mainly diseases affecting the central nervous system, are caused by the expansion of unstable nucleotide repeats. Repeats of sequences like (CAG)
Identifiants
pubmed: 32843153
pii: S0197-4580(20)30244-X
doi: 10.1016/j.neurobiolaging.2020.07.027
pii:
doi:
Substances chimiques
C9orf72 Protein
0
C9orf72 protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
148.e1-148.e7Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.