Short communication: Modulation of fatty acid metabolism improves oxygen tolerance of Bifidobacterium animalis ssp. lactis Probio-M8.

Bifidobacterium animalis / metabolism Fatty Acids / metabolism Gene Expression Profiling Humans Milk, Human / microbiology Oxygen / metabolism Probiotics / metabolism RNA-Seq
Bifidobacterium animalis ssp. lactis Probio-M8 adaptive evolution fatty acids oxidative stress transcriptomic analysis

Journal

Journal of dairy science
ISSN: 1525-3198
Titre abrégé: J Dairy Sci
Pays: United States
ID NLM: 2985126R

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 12 12 2019
accepted: 12 04 2020
pubmed: 31 8 2020
medline: 31 12 2020
entrez: 31 8 2020
Statut: ppublish

Résumé

Bifidobacterium animalis ssp. lactis Probio-M8 is a potential probiotic strain that was isolated from human milk. Previously, we obtained an oxygen-resistant variant (Probio-M8o) of Probio-M8 by an adaptive evolution strategy. In the present study, a comparative transcriptomic analysis of Probio-M8o and Probio-M8 was carried out to reveal the cellular mechanism of the oxygen-resistant phenotype. Using RNA-seq, 210 and 217 differentially expressed genes were identified in Probio-M8o compared with Probio-M8 after oxygen exposure for 30 and 60 min, respectively. The oxygen treatment upregulated a set of genes that encoded proteins responsible for fatty acid biosynthesis. This observation was in good agreement with the composition change in fatty acids at the biochemical level. Our study showed that the oxygen-resistant phenotype could be related to adaptation of fatty acid metabolism.

Identifiants

DOI: 10.3168/jds.2019-18049 PMID: 32861486
pubmed: 32861486
pii: S0022-0302(20)30637-8
doi: 10.3168/jds.2019-18049
pii:
doi:

Substances chimiques

Fatty Acids 0
Oxygen S88TT14065

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8791-8795

Informations de copyright

Copyright © 2020 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Auteurs

Wenyi Zhang (W)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China.

Yuanchi Wang (Y)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China.

Kangning Li (K)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China.

Lai-Yu Kwok (LY)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China.

Wenjun Liu (W)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China.

Heping Zhang (H)

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Key Laboratory of Dairy Products Processing, Ministry of Agriculture, Inner Mongolia Agricultural University, Huhhot 010018, China. Electronic address: hepingdd@vip.sina.com.

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Classifications MeSH

questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes irréguliers à Gram positif › Actinobacteria › Bifidobacterium › Bifidobacterium animalis › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Lipides › Acides gras › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Aliments et boissons › Aliments › Produits laitiers › Lait › Lait humain › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Aliments et boissons › Aliments › Compléments alimentaires › Probiotiques › Short communication: Modulation of fatty acid...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ARN › RNA-Seq › Short communication: Modulation of fatty acid...