Spectroscopic characterization of dipicolinic acid and its photoproducts as thymine photosensitizers.

Energy Transfer Photosensitizing Agents Picolinic Acids Thymine
DNA Laser flash photolysis Photochemistry Spores Triplet excited state

Journal

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533

Informations de publication

Date de publication:
15 Jan 2021
Historique:
received: 24 07 2020
revised: 21 08 2020
accepted: 26 08 2020
pubmed: 15 9 2020
medline: 15 5 2021
entrez: 14 9 2020
Statut: ppublish

Résumé

Dipicolinic acid (DPA), present in large amount in bacterial spores, has been proposed to act as an endogenous photosensitizer in spore photoproduct formation. The proposed mechanism involves a triplet-triplet energy transfer from DPA to thymine. However, up to now, no spectroscopic studies have been performed to determine the interaction between the endogenous compound and the nucleobase, probably due to its photolability in aqueous solutions. Here, triplet excited state properties of DPA are reported together with its bimolecular quenching rate constant by thymidine, k

Identifiants

DOI: 10.1016/j.saa.2020.118898 PMID: 32927302
pubmed: 32927302
pii: S1386-1425(20)30877-5
doi: 10.1016/j.saa.2020.118898
pii:
doi:

Substances chimiques

Photosensitizing Agents 0
Picolinic Acids 0
Thymine QR26YLT7LT
dipicolinic acid UE81S5CQ0G

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

118898

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest Authors declare no conflict of interest.

Auteurs

Giacomo Nardi (G)

Instituto Universitario Mixto de Tecnología Química, Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022, Valencia, Spain.

Mauricio Lineros-Rosa (M)

Instituto Universitario Mixto de Tecnología Química, Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022, Valencia, Spain.

Fabrizio Palumbo (F)

Instituto Universitario Mixto de Tecnología Química, Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022, Valencia, Spain.

Miguel A Miranda (MA)

Instituto Universitario Mixto de Tecnología Química, Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022, Valencia, Spain. Electronic address: mmiranda@qim.upv.es.

Virginie Lhiaubet-Vallet (V)

Instituto Universitario Mixto de Tecnología Química, Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022, Valencia, Spain. Electronic address: lvirgini@itq.upv.es.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Transfert d'énergie › Spectroscopic characterization of dipicolinic...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › Spectroscopic characterization of dipicolinic...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyridines › Acides picoliniques › Spectroscopic characterization of dipicolinic...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Pyrimidinones › Uracile › Thymine › Spectroscopic characterization of dipicolinic...