Cell-Free Approaches for Dental Pulp Tissue Engineering.

Cell homing dental pulp dental pulp stem cells dentin matrix proteins scaffold tissue engineering

Journal

Journal of endodontics
ISSN: 1878-3554
Titre abrégé: J Endod
Pays: United States
ID NLM: 7511484

Informations de publication

Date de publication:
Sep 2020
Historique:
entrez: 20 9 2020
pubmed: 21 9 2020
medline: 23 9 2020
Statut: ppublish

Résumé

In past years, both cell transplantation and cell homing have been explored for dental pulp tissue engineering. Sufficient evidence shows that after cell transplantation, the regeneration of a functional dentin-pulp complex is possible. A new milestone was reached recently. The concept has now been evaluated in clinical studies. However, the approach is afflicted with high efforts and operating expenses; thus cell homing might be a viable alternative. In this article, the latest developments on the recruitment of resident stem cells by dentin-derived growth factors in injectable fibrin-based scaffold materials will be discussed.

Identifiants

pubmed: 32950186
pii: S0099-2399(20)30445-3
doi: 10.1016/j.joen.2020.06.034
pii:
doi:

Types de publication

Journal Article

Langues

eng

Pagination

S143-S149

Informations de copyright

Copyright © 2020 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Auteurs

Kerstin M Galler (KM)

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany. Electronic address: kerstin.galler@ukr.de.

Matthias Widbiller (M)

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

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