An enzyme linked aptamer photoelectrochemical biosensor for Tau-381 protein using AuNPs/MoSe


Journal

Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336

Informations de publication

Date de publication:
05 Jan 2021
Historique:
received: 20 07 2020
revised: 26 09 2020
accepted: 28 09 2020
pubmed: 17 10 2020
medline: 22 6 2021
entrez: 16 10 2020
Statut: ppublish

Résumé

Alzheimer's disease is a worldwide health problem and it has attracted extensive attention. Tau protein is an important biomarker in the pathogenesis of Alzheimer's disease. Herein, we devise a in situ enzyme catalysis generating electron donor photoelectrochemical (PEC) biosensor for Tau-381 protein. Tau-381 protein aptamer is immobilized onto the surface of AuNPs/MoSe

Identifiants

pubmed: 33065402
pii: S0731-7085(20)31552-1
doi: 10.1016/j.jpba.2020.113666
pii:
doi:

Substances chimiques

Smart Materials 0
tau Proteins 0
Gold 7440-57-5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113666

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declared that they have no conflicts of interest to this work.

Auteurs

Xu Hun (X)

Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. Electronic address: hunxuprof@outlook.com.

Xiaohui Kong (X)

Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

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Classifications MeSH