Transcriptome Profiling of Human Monocyte-Derived Macrophages Upon CCL2 Neutralization Reveals an Association Between Activation of Innate Immune Pathways and Restriction of HIV-1 Gene Expression.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 30 04 2020
accepted: 05 08 2020
entrez: 19 10 2020
pubmed: 20 10 2020
medline: 7 5 2021
Statut: epublish

Résumé

Macrophages are key targets of human immunodeficiency virus type 1 (HIV-1) infection and main producers of the proinflammatory chemokine CC chemokine ligand 2 (CCL2), whose expression is induced by HIV-1 both

Identifiants

pubmed: 33072075
doi: 10.3389/fimmu.2020.02129
pmc: PMC7531389
doi:

Substances chimiques

Antibodies, Neutralizing 0
CCL2 protein, human 0
Chemokine CCL2 0
MIRN155 microRNA, human 0
MicroRNAs 0
NF-kappa B 0
Proteins 0
RNA, Viral 0
APOBEC3A protein, human EC 3.5.4.5
Cytidine Deaminase EC 3.5.4.5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2129

Informations de copyright

Copyright © 2020 Covino, Kaczor-Urbanowicz, Lu, Chiantore, Fiorucci, Vescio, Catapano, Purificato, Galluzzo, Amici, Andreotti, Gauzzi, Pellegrini and Fantuzzi.

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Auteurs

Daniela Angela Covino (DA)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Karolina Elżbieta Kaczor-Urbanowicz (KE)

UCLA Section of Oral Biology, Division of Oral Biology & Medicine, Center for Oral and Head/Neck Oncology Research, Center for the Health Sciences, UCLA School of Dentistry, University of California at Los Angeles, Los Angeles, CA, United States.
UCLA Institute for Quantitative and Computational Biosciences, University of California at Los Angeles, Los Angeles, CA, United States.

Jing Lu (J)

UCLA Institute for Quantitative and Computational Biosciences, University of California at Los Angeles, Los Angeles, CA, United States.

Maria Vincenza Chiantore (MV)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Gianna Fiorucci (G)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Institute of Molecular Biology and Pathology, CNR, Rome, Italy.

Maria Fenicia Vescio (MF)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Laura Catapano (L)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Cristina Purificato (C)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Clementina Maria Galluzzo (CM)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Roberta Amici (R)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Mauro Andreotti (M)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Maria Cristina Gauzzi (MC)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Matteo Pellegrini (M)

UCLA Institute for Quantitative and Computational Biosciences, University of California at Los Angeles, Los Angeles, CA, United States.

Laura Fantuzzi (L)

National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

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Classifications MeSH