[Early outcomes following lung transplantation in patients aged 65 years and older].
Résultats précoces de la transplantation pulmonaire chez les patients âgés de 65 ans et plus.
Age Factors
Age of Onset
Aged
Aged, 80 and over
Female
France
/ epidemiology
Graft Survival
Humans
Lung Diseases, Interstitial
/ epidemiology
Lung Diseases, Obstructive
/ epidemiology
Lung Transplantation
/ adverse effects
Male
Paris
/ epidemiology
Postoperative Period
Primary Graft Dysfunction
/ epidemiology
Retrospective Studies
Survival Rate
Time Factors
Treatment Outcome
Chronic respiratory failure
Elderly
Insuffisance respiratoire chronique
Lung transplantation
Patients âgés
Transplantation pulmonaire
Journal
Revue des maladies respiratoires
ISSN: 1776-2588
Titre abrégé: Rev Mal Respir
Pays: France
ID NLM: 8408032
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
30
08
2019
accepted:
28
08
2020
pubmed:
8
11
2020
medline:
17
12
2020
entrez:
7
11
2020
Statut:
ppublish
Résumé
The number of lung transplantations performed is increasing worldwide. With an improved experience and outcomes, the age of the recipient on its own has ceased to be an absolute contra-indication. We report our first experience with lung transplantation in patients aged 65 years or older. From January 2014 to March 2019, the files of patients aged 65 years or older undergoing lung transplantation were retrospectively reviewed. During the study period, 241 patients underwent lung transplantation in Bichat hospital (Paris, France), including 25 recipients aged 65 years or older. Underlying diagnoses were interstitial (72%) and obstructive (28%) disease. The rate of single lung transplantation was 80%. Sixteen patients required ECMO assistance during the procedure. Early complications were mostly grade III primary graft dysfunction (12%) and cellular rejection (20%). Overall one-year survival rate was 76%. After a careful selection of the recipients, the early results of our retrospective single center series are encouraging. We continue to consider lung transplantation in rigorously selected recipients of aged 65 years and more.
Identifiants
pubmed: 33158640
pii: S0761-8425(20)30295-3
doi: 10.1016/j.rmr.2020.08.012
pii:
doi:
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
769-775Informations de copyright
Copyright © 2020 SPLF. Published by Elsevier Masson SAS. All rights reserved.