Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS.


Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
27 11 2020
Historique:
received: 01 04 2020
revised: 02 10 2020
accepted: 06 11 2020
entrez: 28 11 2020
pubmed: 29 11 2020
medline: 28 9 2021
Statut: ppublish

Résumé

Inflammatory caspase-dependent cytosolic lipopolysaccharide (LPS) sensing is a critical arm of host defense against bacteria. How pathogens overcome this pathway to establish infections is largely unknown. Enterohemorrhagic

Identifiants

pubmed: 33246946
pii: 5/53/eabc0217
doi: 10.1126/sciimmunol.abc0217
pmc: PMC7717664
mid: NIHMS1646281
pii:
doi:

Substances chimiques

Gsdmd protein, mouse 0
Inflammasomes 0
Intracellular Signaling Peptides and Proteins 0
Lipopolysaccharides 0
Phosphate-Binding Proteins 0
Shiga Toxin 1 0
Shiga Toxin 2 0
Viral Proteins 0
Virulence Factors 0
Casp4 protein, mouse EC 3.4.22.-
Caspases, Initiator EC 3.4.22.-

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI132850
Pays : United States

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Références

Lancet. 2010 Oct 23;376(9750):1428-35
pubmed: 20971366
Pediatr Res. 2001 Aug;50(2):163-71
pubmed: 11477199
Infect Immun. 2010 Nov;78(11):4488-99
pubmed: 20732996
Lancet. 2005 Mar 19-25;365(9464):1073-86
pubmed: 15781103
Nature. 2018 Nov;563(7733):705-709
pubmed: 30464342
Infect Immun. 1992 Feb;60(2):485-90
pubmed: 1730480
FEMS Microbiol Lett. 2006 Feb;255(2):187-202
pubmed: 16448495
Oxid Med Cell Longev. 2016;2016:3578368
pubmed: 26798420
Nature. 2016 Jul 7;535(7610):111-6
pubmed: 27281216
Infect Immun. 2016 Dec 29;85(1):
pubmed: 27795361
Dev Cell. 2004 Aug;7(2):217-28
pubmed: 15296718
J Leukoc Biol. 2006 Feb;79(2):397-407
pubmed: 16301326
PLoS Pathog. 2019 Jan 10;15(1):e1007494
pubmed: 30629725
Nat Immunol. 2019 May;20(5):527-533
pubmed: 30962589
J Clin Invest. 2015 Feb;125(2):469-77
pubmed: 25642707
Science. 2016 Jun 3;352(6290):1232-6
pubmed: 27103670
Arch Pediatr Adolesc Med. 2002 Sep;156(9):893-900
pubmed: 12197796
Front Immunol. 2015 Nov 10;6:570
pubmed: 26617605
Nature. 2000 Jul 6;406(6791):64-7
pubmed: 10894541
Cell. 2018 May 3;173(4):920-933.e13
pubmed: 29576451
Infect Immun. 2015 Oct 26;84(1):172-86
pubmed: 26502906
Cell. 2010 Mar 19;140(6):821-32
pubmed: 20303873
PLoS Pathog. 2015 Sep 02;11(9):e1005121
pubmed: 26332984
FASEB J. 2001 Jul;15(9):1493-506
pubmed: 11427481
Nature. 2014 Oct 9;514(7521):187-92
pubmed: 25119034
Cell Host Microbe. 2019 Oct 9;26(4):542-550.e5
pubmed: 31561965
Toxins (Basel). 2010 Jun;2(6):1515-35
pubmed: 22069648
Nat Commun. 2020 Jun 24;11(1):3276
pubmed: 32581219
Microbiol Spectr. 2014 Aug;2(4):EHEC-0007-2013
pubmed: 26104209
Science. 2013 Feb 22;339(6122):975-8
pubmed: 23348507
Cell Rep. 2018 Nov 6;25(6):1525-1536.e7
pubmed: 30404007
Science. 2013 Sep 13;341(6151):1246-9
pubmed: 23887873
Nat Rev Microbiol. 2004 Feb;2(2):123-40
pubmed: 15040260
Front Cell Infect Microbiol. 2013 Nov 26;3:76
pubmed: 24324933
Cell. 2012 Aug 3;150(3):606-19
pubmed: 22819539
Nature. 2001 Jan 25;409(6819):529-33
pubmed: 11206551
Vaccine. 2006 Feb 20;24(8):1142-8
pubmed: 16198455
Future Microbiol. 2017 Aug;12:905-914
pubmed: 28434234
Infect Immun. 2015 Oct 19;84(1):149-61
pubmed: 26483409
Blood. 1996 Jul 1;88(1):174-83
pubmed: 8704172
Toxins (Basel). 2011 Jun;3(6):626-39
pubmed: 22069729
Nature. 2016 Jul 06;535(7610):153-8
pubmed: 27383986
Nat Immunol. 2010 May;11(5):395-402
pubmed: 20351692
Cell Host Microbe. 2013 May 15;13(5):570-583
pubmed: 23684308
J Clin Invest. 2012 Nov;122(11):4012-24
pubmed: 23041631
J Biol Chem. 1987 Jun 25;262(18):8834-9
pubmed: 3298243
Kidney Int. 2006 Dec;70(12):2049-51
pubmed: 17136129
J Clin Microbiol. 2012 Sep;50(9):2951-63
pubmed: 22760050
Cell Microbiol. 2011 Oct;13(10):1479-96
pubmed: 21722286
J Immunol. 2012 Dec 15;189(12):5508-12
pubmed: 23144495
Infect Immun. 2006 Mar;74(3):1984-8
pubmed: 16495579
Nature. 2015 Oct 29;526(7575):666-71
pubmed: 26375259
Nature. 2011 Oct 16;479(7371):117-21
pubmed: 22002608
Nature. 2015 Oct 29;526(7575):660-5
pubmed: 26375003
Cell. 2016 May 19;165(5):1106-1119
pubmed: 27156449
Biochemistry. 2010 Mar 2;49(8):1649-57
pubmed: 20092352
Cell. 2020 Mar 5;180(5):941-955.e20
pubmed: 32109412
Science. 2013 Sep 13;341(6151):1250-3
pubmed: 24031018
Cell Host Microbe. 2008 Sep 11;4(3):198-208
pubmed: 18779046
Nature. 2014 Sep 11;513(7517):237-41
pubmed: 24919149

Auteurs

Morena S Havira (MS)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Atri Ta (A)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Puja Kumari (P)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Chengliang Wang (C)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Ashley J Russo (AJ)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Jianbin Ruan (J)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Vijay A Rathinam (VA)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.

Sivapriya Kailasan Vanaja (SK)

Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA. kailasanvanaja@uchc.edu.

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Classifications MeSH