Foodborne botulism presenting as small bowel obstruction: a case report.


Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
12 Jan 2021
Historique:
received: 03 11 2020
accepted: 30 12 2020
entrez: 13 1 2021
pubmed: 14 1 2021
medline: 30 1 2021
Statut: epublish

Résumé

Small bowel obstruction is one of the leading reasons for accessing to the Emergency Department. Food poisoning from Clostridium botulinum has emerged as a very rare potential cause of small bowel obstruction. The relevance of this case report regards the subtle onset of pathognomonic neurological symptoms, which can delay diagnosis and subsequent life-saving treatment. A 24-year-old man came to our Emergency Department complaining of abdominal pain, fever and sporadic self-limiting episodes of diplopia, starting 4 days earlier. Clinical presentation and radiological imaging suggested a case of small bowel obstruction. Non-operative management was adopted, which was followed by worsening of neurological signs. On specifically questioning the patient, we discovered that his parents had experienced similar, but milder symptoms. The patient also recalled eating home-made preserves some days earlier. A clinical diagnosis of foodborne botulism was established and antitoxin was promptly administered with rapid clinical resolution. Though very rare, botulism can mimic small bowel obstruction, and could be associated with a rapid clinical deterioration if misdiagnosed. An accurate family history, frequent clinical reassessments and involvement of different specialists can guide to identify this unexpected diagnosis.

Sections du résumé

BACKGROUND BACKGROUND
Small bowel obstruction is one of the leading reasons for accessing to the Emergency Department. Food poisoning from Clostridium botulinum has emerged as a very rare potential cause of small bowel obstruction. The relevance of this case report regards the subtle onset of pathognomonic neurological symptoms, which can delay diagnosis and subsequent life-saving treatment.
CASE PRESENTATION METHODS
A 24-year-old man came to our Emergency Department complaining of abdominal pain, fever and sporadic self-limiting episodes of diplopia, starting 4 days earlier. Clinical presentation and radiological imaging suggested a case of small bowel obstruction. Non-operative management was adopted, which was followed by worsening of neurological signs. On specifically questioning the patient, we discovered that his parents had experienced similar, but milder symptoms. The patient also recalled eating home-made preserves some days earlier. A clinical diagnosis of foodborne botulism was established and antitoxin was promptly administered with rapid clinical resolution.
CONCLUSIONS CONCLUSIONS
Though very rare, botulism can mimic small bowel obstruction, and could be associated with a rapid clinical deterioration if misdiagnosed. An accurate family history, frequent clinical reassessments and involvement of different specialists can guide to identify this unexpected diagnosis.

Identifiants

pubmed: 33435866
doi: 10.1186/s12879-020-05759-0
pii: 10.1186/s12879-020-05759-0
pmc: PMC7801865
doi:

Substances chimiques

Botulinum Antitoxin 0
Immunologic Factors 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

55

Références

Lancet. 1996 Dec 7;348(9041):1594
pubmed: 8950913
Toxins (Basel). 2020 Jan 24;12(2):
pubmed: 31991691
AJR Am J Roentgenol. 2005 Oct;185(4):1036-44
pubmed: 16177429
Am J Surg. 2000 Jul;180(1):33-6
pubmed: 11036136
Euro Surveill. 2017 Jun 15;22(24):
pubmed: 28661393
Eur J Clin Microbiol Infect Dis. 2007 Jun;26(6):385-94
pubmed: 17516104
CMAJ. 2008 Oct 21;179(9):927-9
pubmed: 18936457
World J Emerg Surg. 2018 Jun 19;13:24
pubmed: 29946347

Auteurs

Alberto Friziero (A)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Cosimo Sperti (C)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy. cosimo.sperti@unipd.it.

Gianfranco Da Dalt (G)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Nicola Baldan (N)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Gianpietro Zanchettin (G)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Pasquale Auricchio (P)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Laura Gavagna (L)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Andrea Grego (A)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Giulia Capelli (G)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

Stefano Merigliano (S)

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

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Classifications MeSH