Ethylzingerone, a Novel Compound with Antifungal Activity.
Candida albicans
HEPB
antifungal
cosmetics
ethylzingerone
hydroxyethoxyphenyl butanone
mechanism of action
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
18 03 2021
18 03 2021
Historique:
received:
04
01
2021
accepted:
04
01
2021
pubmed:
21
1
2021
medline:
22
6
2021
entrez:
20
1
2021
Statut:
epublish
Résumé
Preservatives increase the shelf life of cosmetic products by preventing growth of contaminating microbes, including bacteria and fungi. In recent years, the Scientific Committee on Consumer Safety (SCCS) has recommended the ban or restricted use of a number of preservatives due to safety concerns. Here, we characterize the antifungal activity of ethylzingerone (hydroxyethoxyphenyl butanone [HEPB]), an SCCS-approved new preservative for use in rinse-off, oral care, and leave-on cosmetic products. We show that HEPB significantly inhibits growth of
Identifiants
pubmed: 33468481
pii: AAC.02711-20
doi: 10.1128/AAC.02711-20
pmc: PMC8097443
pii:
doi:
Substances chimiques
Antifungal Agents
0
Cosmetics
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2021 American Society for Microbiology.
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