Optimisation of microwave-assisted extraction and functional elucidation of bioactive compounds from Cola nitida pod.
Cola nitida
antioxidants
microstructure
microwave extraction
total phenolic content (TPC)
Journal
Phytochemical analysis : PCA
ISSN: 1099-1565
Titre abrégé: Phytochem Anal
Pays: England
ID NLM: 9200492
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
revised:
15
01
2021
received:
15
09
2020
accepted:
16
01
2021
pubmed:
15
2
2021
medline:
18
8
2021
entrez:
14
2
2021
Statut:
ppublish
Résumé
The quality characteristics and stability of phenolic by-products from Cola nitida wastes are critical factors for drug formulation and food nutraceutical applications. In this study, the effect of electromagnetic-based microwave-reflux extraction on the total phenolic content, antioxidant capacity, morphological characteristics, physisorption and chromatographic phenolic profiles were successfully investigated. These physicochemical analyses are often employed in the standardisation of dried herbal and food nutraceutical products. In this study, the electromagnetic-based extraction process was optimised using the Box-Behnken design. The oleoresin bio-products were subsequently characterised to determine the total phenolic content, morphological and microstructural degradation. These analyses were conducted to elucidate the effect of the microwave heating on the C. nitida pod powder. From the predicted response, the optimal percentage yield was achieved at 26.20% under 5.39 min of irradiation time, 440 W microwave power and oven temperature of 55°C. Moreover, the rapid estimation of the phenolic content and antioxidant capacity were recorded at 124.84 ± 0.064 mg gallic acid equivalent (GAE)/g dry weight (d.w.) and 6.93 ± 0.34 μg/mL, respectively. The physicochemical characterisation results from the Fourier-transform infrared spectroscopy, field emission scanning electron microscopy and physisorption analyses showed remarkable changes in the micro-surface area (13.66%) characteristics. The recorded optimal conditions established a basis for future scale-up of microwave extraction parameters with a potential for maximum yield. The physiochemical characterisation revealed the functional characteristics of C. nitida and their tolerance to microwave heating.
Substances chimiques
Antioxidants
0
Phenols
0
Gallic Acid
632XD903SP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
850-858Informations de copyright
© 2021 John Wiley & Sons, Ltd.
Références
Jean Marc N, Daouda N, Kouakou Nestor K, Georges N’Guessan A. Typology use and process of cola nut (Cola nitida) produced in Cote d'Ivoire. Adv Crop Sci Technol. 2018;6(4):371-380. https://doi.org/10.4172/2329-8863.1000379
Asogwa EU, Otuonye AH, Mokwunye FC, Oluyole KA, Ndubuaku TC, Uwagboe EO. Kolanut production, processing and marketing in the south-eastern states of Nigeria. African J Plant Sci. 2011;5(10):547-551.
Durand D-N. Indigenous knowledge and socioeconomic values of three Kola species (Cola nitida, Cola acuminata and Garcinia kola) used in southern Benin. Eur Sci J. 2015;11(36):206-227.
Abalaka ME. Investigation into the medicinal values of cola species-Cola nitida and Cola acuminata. Sci Agric. 2015;10(1):31-34. https://doi.org/10.15192/pscp.sa.2015.10.1.3134
Olalere OA, Abdurahman HN, Gan CY. Microwave-enhanced extraction and mass spectrometry fingerprints of polyphenolic constituents in Sesamum indicum leaves. Ind Crop Prod. 2019;131(August 2018):151-159. https://doi.org/10.1016/j.indcrop.2018.12.024
Adesanwo JK, Ogundele SB, Akinpelu DA, McDonald AG. Chemical analyses, antimicrobial and antioxidant activities of extracts from Cola nitida seed. J Explor Res Pharmacol. 2017;2(3):67-77. https://doi.org/10.14218/jerp.2017.00015
Bukola FT. Effects of Kolanut husk formulated feed at graded levels on growth performance and health of Ross broilers with and without enzyme inclusion. ACTA Sci Agric. 2019;3(2):105-113.
Olalere OA, Abdurahman NH, Yunus R, Bin M, Alara OR, Gan CY. Synergistic intermittent heating and energy intensification of scale-up parameters in an optimized microwave extraction process. Chem Eng Process - Process Intensif. 2018;132(August):160-168. https://doi.org/10.1016/j.cep.2018.08.011
Olalere OA, Gan C-Y, Abdurahman HN, Ahmad MS, Aziz Qannaf Zaid OAH. Microstructural and microchemical characterization of valorized Cola nitida pod wastes microstructural and microchemical characterization of valorized Cola nitida pod wastes. Chem Data Collect. 2020;26:1-11. https://doi.org/10.1016/j.cdc.2020.100356
Olalere OA, Gan CY. Multi-step reflux extraction of bio-pharmaceutical phenolic bioactives from balsam apple (Momordica). J Taibah Univ Sci. 2020;14(1):227-234. https://doi.org/10.1080/16583655.2020.1721722
Zhang QW, Lin LG, Ye WC. Techniques for extraction and isolation of natural products: a comprehensive review. Chinese Med (United Kingdom). 2018;13(1):1-26. https://doi.org/10.1186/s13020-018-0177-x
Zhao P, Liu C, Qu W, et al. Effect of temperature and microwave power levels on microwave drying kinetics of Zhaotong lignite. Processes. 2019;7(2):74-92. https://doi.org/10.3390/pr7020074
Veggi PC, Martinez J, Meireles MAA. Microwave-Assisted Extraction for Bioactive Compounds. Vol 238. Berlin: Springer Science & Business Media; 2013. https://doi.org/10.1007/978-1-4614-4830-3
Abdurahman NH. A comparative review of conventional and microwave assisted extraction in capsaicin isolation from chili pepper. Aust J Bas Appl Sci. 2016;10(June):263-275.
Olalere OA, Gan CY. Microwave reflux extraction-An alternative approach for phenolic-rich oleoresins extraction from functional plants. In: Green Sustainable Process for Chemical and Environmental Engineering and Science. Microwaves in Organic Synthesis. Amsterdam: Elsevier; 2021:661-678.
Alara OR, Abdul Mudalip SK, Olalere OA. Optimization of mangiferin extracted from Phaleria macrocarpa fruits using response surface methodology. J Appl Res Med Aromat Plants. 2017;5:82-87. https://doi.org/10.1016/j.jarmap.2017.02.002
Olalere OA, Abdurahman HN, Mohd R, Alara OR, Ahmad MM, Zaki YH. Parameter study, antioxidant activities, morphological and functional characteristics in microwave extraction of medicinal oleoresins from black and white pepper. J Taibah Univ Sci. 2018;12(6):1-8. https://doi.org/10.1080/16583655.2018.1515323
Alara OR, Abdurahman NH, Mudalip SKA, Olalere OA. Characterization and effect of extraction solvents on the yield and total phenolic content from Vernonia amygdalina leaves. J Food Meas Charact. 2017;12(1):311-316. https://doi.org/10.1007/s11694-017-9642-y
Johari MA, Khong HY. Total phenolic content and antioxidant and antibacterial activities of Pereskia bleo. Adv Pharm Sci. 2019;2019:1-4. https://doi.org/10.1155/2019/7428593
Olmedo-Suarez MA, Canizares-Macías MP. Method for the production of natural vanilla extracts using a conventional microwave oven. Curr Microw Chem. 2015;2(1):24-31. https://doi.org/10.2174/221333560201150212103234
Olalere OA, Abdurahman NH, Yunus R, Bin M, Alara OR, Kabbashi NA. Chemical fingerprinting of biologically active compounds and morphological transformation during microwave reflux extraction of black pepper. Chem Data Collect. 2018;17-18(October):339-344. https://doi.org/10.1016/j.cdc.2018.10.007
Dahmoune F, Spigno G, Moussi K, Remini H, Cherbal A, Madani K. Pistacia lentiscus leaves as a source of phenolic compounds: microwave-assisted extraction optimized and compared with ultrasound-assisted and conventional solvent extraction. Ind Crop Prod. 2014;61:31-40. https://doi.org/10.1016/j.indcrop.2014.06.035
Kullu J, Dutta A, Constales D. Experimental and modeling studies on microwave-assisted extraction of mangiferin from Curcuma amada. 3 Biotech. 2013;5:1-14. https://doi.org/10.1007/s13205-013-0125-5
Xu L-LZ, Xu JG. Comparative study on antioxidant activity of essential oil from white and black pepper. Eur J Food Sci Technol. 2015;3(3):10-16.
Rajkovic K, Pekmezovic M, Barac A, Nikodinovic-Runic J, Arsenijević VA. Inhibitory effect of thyme and cinnamon essential oils on Aspergillus flavus: optimization and activity prediction model development. Ind Crop Prod. 2015;65(8):7-13. https://doi.org/10.1016/j.indcrop.2014.11.039
Subroto E, Manurung R, Heeres HJ, Broekhuis AA. Optimization of mechanical oil extraction from Jatropha curcas L. kernel using response surface method. Ind Crop Prod. 2015;63:294-302. https://doi.org/10.1016/j.indcrop.2014.08.050
AbdErahman A, Olalere OA, Ahmed AE, et al. Comparative analysis of polyphenolic and antioxidant constituents in dried seedlings and seedless Acacia nilotica fruits. J Anal Test. 2018;2(4):352-355. https://doi.org/10.1007/s41664-018-0071-7
Alara OR, Abdurahman NH, Olalere OA. Ethanolic extraction of flavonoids, phenolics and antioxidants from Vernonia amygdalina leaf using two-level factorial design. J King Saud Univ - Sci. 2017;32(August):7-16. https://doi.org/10.1016/j.jksus.2017.08.001
Frankenberger LD, Mora T, de Siqueira CD, et al. UPLC-ESI-QTOF-MS2 characterisation of Cola nitida resin fractions with inhibitory effects on NO and TNF-α released by LPS-activated J774 macrophage and on Trypanosoma cruzi and Leishmania amazonensis. Phytochem Anal. 2018;29(6):577-589. https://doi.org/10.1002/pca.2771
Oboh G, Nwokocha KE, Akinyemi AJ, Ademiluyi AO. Inhibitory effect of polyphenolic-rich extract from Cola nitida (Kolanut) seed on key enzyme linked to type 2 diabetes and Fe2+ induced lipid peroxidation in rat pancreas in vitro. Asian Pac J Trop Biomed. 2014;4(Suppl 1):S405-S412. https://doi.org/10.12980/APJTB.4.2014C75
Momo CEN, Ngwa AF, Dongmo GIF, Oben JE. Antioxidant properties and α-amylase inhibition of Terminalia superba, Albizia sp., Cola nitida, Cola odorata and Harungana madagascarensis used in the management of diabetes in Cameroon. J Heal Sci. 2009;55(5):732-738. https://doi.org/10.1248/jhs.55.732