Pulmonary Abnormalities in Liver Disease: Relevance to Transplantation and Outcome.
Adult
Asthma
/ diagnosis
COVID-19
/ diagnosis
Child
Cystic Fibrosis
End Stage Liver Disease
/ complications
Hepatopulmonary Syndrome
/ diagnosis
Humans
Hypertension, Portal
/ complications
Hypertension, Pulmonary
/ drug therapy
Liver Cirrhosis
/ complications
Liver Transplantation
/ methods
Lung Diseases
/ complications
Mass Screening
Patient Selection
/ ethics
Prognosis
Pulmonary Disease, Chronic Obstructive
/ diagnosis
Respiratory Function Tests
/ methods
SARS-CoV-2
/ genetics
Sarcoidosis
/ diagnosis
Survival Rate
/ trends
Telangiectasia, Hereditary Hemorrhagic
/ diagnosis
alpha 1-Antitrypsin Deficiency
/ diagnosis
Journal
Hepatology (Baltimore, Md.)
ISSN: 1527-3350
Titre abrégé: Hepatology
Pays: United States
ID NLM: 8302946
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
17
01
2021
received:
15
11
2020
accepted:
08
02
2021
pubmed:
27
2
2021
medline:
23
9
2021
entrez:
26
2
2021
Statut:
ppublish
Résumé
Pulmonary disease in liver cirrhosis and portal hypertension (PH) constitutes a challenging clinical scenario and may have important implications with regard to prognosis, liver transplantation (LT) candidacy, and post-LT outcome. Pre-LT evaluation should include adequate screening for pulmonary diseases that may occur concomitantly with liver disease as well as for those that may arise as a complication of end-stage liver disease and PH, given that either may jeopardize safe LT and successful outcome. It is key to discriminate those patients who would benefit from LT, especially pulmonary disorders that have been reported to resolve post-LT and are considered "pulmonary indications" for transplant, from those who are at increased mortality risk and in whom LT is contraindicated. In conclusion, in this article, we review the impact of several pulmonary disorders, including cystic fibrosis, alpha 1-antitrypsin deficiency, hereditary hemorrhagic telangiectasia, sarcoidosis, coronavirus disease 2019, asthma, chronic obstructive pulmonary disease, pulmonary nodules, interstitial lung disease, hepatic hydrothorax, hepatopulmonary syndrome, and portopulmonary hypertension, on post-LT survival, as well as the reciprocal impact of LT on the evolution of lung function.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1674-1686Subventions
Organisme : Fonds Wetenschappelijk Onderzoek
Informations de copyright
© 2021 by the American Association for the Study of Liver Diseases.
Références
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