Breast tumours maintain a reservoir of subclonal diversity during expansion.
Base Sequence
Breast Neoplasms
/ genetics
Cell Line, Tumor
Cell Lineage
Cell Proliferation
Chromosome Aberrations
Clone Cells
/ metabolism
DNA Copy Number Variations
/ genetics
DNA Mutational Analysis
Evolution, Molecular
Genomic Instability
/ genetics
Humans
Loss of Heterozygosity
/ genetics
Models, Genetic
Mutation Rate
Single Molecule Imaging
Single-Cell Analysis
Triple Negative Breast Neoplasms
/ genetics
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
13
05
2020
accepted:
12
02
2021
pubmed:
26
3
2021
medline:
1
9
2021
entrez:
25
3
2021
Statut:
ppublish
Résumé
Our knowledge of copy number evolution during the expansion of primary breast tumours is limited
Identifiants
pubmed: 33762732
doi: 10.1038/s41586-021-03357-x
pii: 10.1038/s41586-021-03357-x
pmc: PMC8049101
mid: NIHMS1673613
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
302-308Subventions
Organisme : NCI NIH HHS
ID : R01 CA236864
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States
Organisme : NCI NIH HHS
ID : U54 CA143798
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA240526
Pays : United States
Organisme : Arthritis Research UK
ID : FC001202
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : FC001202
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
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