Nicholas E Navin

Affiliations

Department of Genetics and Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Publications (18)

Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells.

The Journal of experimental medicine

Avec: Teresa Manzo , Boone M Prentice , Kristin G Anderson , Ayush Raman , Aislyn Schalck , Gabriela S Codreanu , Carina B Nava Lauson , Silvia Tiberti , Andrea Raimondi , Marissa A Jones , Michelle Reyzer , Breanna M Bates , Jeffrey M Spraggins , Nathan H Patterson , John A McLean , Kunal Rai , Carlo Tacchetti , Sara Tucci , Jennifer A Wargo , Simona Rodighiero , Karen Clise-Dwyer , Stacy D Sherrod , Michael Kim , Nicholas E Navin , Richard M Caprioli , Philip D Greenberg , Giulio Draetta , Luigi Nezi

Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing.

Genome biology

Avec: Naveen Ramesh , Emi Sei , Pei Ching Tsai , Shanshan Bai , Yuehui Zhao , Patricia Troncoso , Paul G Corn , Christopher Logothetis , Amado J Zurita , Nicholas E Navin

Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer.

Nature cancer

Avec: Pat Gulhati , Aislyn Schalck , Shan Jiang , Xiaoying Shang , Chang-Jiun Wu , Pingping Hou , Sharia Hernandez Ruiz , Luisa Solis Soto , Edwin Parra , Haoqiang Ying , Jincheng Han , Prasenjit Dey , Jun Li , Pingna Deng , Emi Sei , Dean Y Maeda , John A Zebala , Denise J Spring , Michael Kim , Huamin Wang , Anirban Maitra , Dirk Moore , Karen Clise-Dwyer , Y Alan Wang , Nicholas E Navin , Ronald A DePinho

Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Paymaneh D Malihi , Ryon P Graf , Angel Rodriguez , Naveen Ramesh , Jerry Lee , Ramsay Sutton , Rhett Jiles , Carmen Ruiz Velasco , Emi Sei , Anand Kolatkar , Christopher Logothetis , Nicholas E Navin , Paul Corn , Ana M Aparicio , Ryan Dittamore , James Hicks , Peter Kuhn , Amado J Zurita

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.

Nature genetics

Avec: Esther H Lips , Tapsi Kumar , Anargyros Megalios , Lindy L Visser , Michael Sheinman , Angelo Fortunato , Vandna Shah , Marlous Hoogstraat , Emi Sei , Diego Mallo , Maria Roman-Escorza , Ahmed A Ahmed , Mingchu Xu , Alexandra W van den Belt-Dusebout , Wim Brugman , Anna K Casasent , Karen Clements , Helen R Davies , Liping Fu , Anita Grigoriadis , Timothy M Hardman , Lorraine M King , Marielle Krete , Petra Kristel , Michiel de Maaker , Carlo C Maley , Jeffrey R Marks , Brian A Menegaz , Lennart Mulder , Frank Nieboer , Salpie Nowinski , Sarah Pinder , Jelmar Quist , Carolina Salinas-Souza , Michael Schaapveld , Marjanka K Schmidt , Abeer M Shaaban , Rana Shami , Mathini Sridharan , John Zhang , Hilary Stobart , Deborah Collyar , Serena Nik-Zainal , Lodewyk F A Wessels , E Shelley Hwang , Nicholas E Navin , P Andrew Futreal , Auteur inconnu , Alastair M Thompson , Jelle Wesseling , Elinor J Sawyer

SCOPIT: sample size calculations for single-cell sequencing experiments.

BMC bioinformatics

Avec: Alexander Davis , Ruli Gao , Nicholas E Navin

Breast tumours maintain a reservoir of subclonal diversity during expansion.

Nature

Avec: Darlan C Minussi , Michael D Nicholson , Hanghui Ye , Alexander Davis , Kaile Wang , Toby Baker , Maxime Tarabichi , Emi Sei , Haowei Du , Mashiat Rabbani , Cheng Peng , Min Hu , Shanshan Bai , Yu-Wei Lin , Aislyn Schalck , Asha Multani , Jin Ma , Thomas O McDonald , Anna Casasent , Angelica Barrera , Hui Chen , Bora Lim , Banu Arun , Funda Meric-Bernstam , Peter Van Loo , Franziska Michor , Nicholas E Navin

Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes.

Nature biotechnology

Avec: Ruli Gao , Shanshan Bai , Ying C Henderson , Yiyun Lin , Aislyn Schalck , Yun Yan , Tapsi Kumar , Min Hu , Emi Sei , Alexander Davis , Fang Wang , Simona F Shaitelman , Jennifer Rui Wang , Ken Chen , Stacy Moulder , Stephen Y Lai , Nicholas E Navin

Spatial charting of single-cell transcriptomes in tissues.

Nature biotechnology

Avec: Runmin Wei , Siyuan He , Shanshan Bai , Emi Sei , Min Hu , Alastair Thompson , Ken Chen , Savitri Krishnamurthy , Nicholas E Navin

Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

Nature reviews. Cancer

Avec: Anna K Casasent , Mathilde M Almekinders , Charlotta Mulder , Proteeti Bhattacharjee , Deborah Collyar , Alastair M Thompson , Jos Jonkers , Esther H Lips , Jacco van Rheenen , E Shelley Hwang , Serena Nik-Zainal , Nicholas E Navin , Jelle Wesseling , Auteur inconnu

Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program.

Cancer discovery

Avec: Jovanka Gencel-Augusto , Xiaoping Su , Yuan Qi , Elizabeth M Whitley , Vinod Pant , Shunbin Xiong , Vrutant Shah , Jerome Lin , Encarnacion Perez , Marta L Fiorotto , Iqbal Mahmud , Abhinav K Jain , Philip L Lorenzi , Nicholas E Navin , Ellen R Richie , Guillermina Lozano

Archival single-cell genomics reveals persistent subclones during DCIS progression.

Cell

Avec: Kaile Wang , Tapsi Kumar , Junke Wang , Darlan Conterno Minussi , Emi Sei , Jianzhuo Li , Tuan M Tran , Aatish Thennavan , Min Hu , Anna K Casasent , Zhenna Xiao , Shanshan Bai , Lei Yang , Lorraine M King , Vandna Shah , Petra Kristel , Carolien L van der Borden , Jeffrey R Marks , Yuehui Zhao , Amado J Zurita , Ana Aparicio , Brian Chapin , Jie Ye , Jianjun Zhang , Don L Gibbons , Auteur inconnu , Ellinor Sawyer , Alastair M Thompson , Andrew Futreal , E Shelley Hwang , Jelle Wesseling , Esther H Lips , Nicholas E Navin

Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response.

Nature genetics

Avec: Kevin C Johnson , Kevin J Anderson , Elise T Courtois , Amit D Gujar , Floris P Barthel , Frederick S Varn , Diane Luo , Martine Seignon , Eunhee Yi , Hoon Kim , Marcos R H Estecio , Dacheng Zhao , Ming Tang , Nicholas E Navin , Rahul Maurya , Chew Yee Ngan , Niels Verburg , Philip C de Witt Hamer , Ketan Bulsara , Michael L Samuels , Sunit Das , Paul Robson , Roel G W Verhaak

Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility.

Molecular cell

Avec: Kaile Wang , Zhenna Xiao , Yun Yan , Rui Ye , Min Hu , Shanshan Bai , Emi Sei , Yawei Qiao , Hui Chen , Bora Lim , Steven H Lin , Nicholas E Navin

A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties.

The Journal of molecular diagnostics : JMD

Avec: Mariam T Mathew , Austin Antoniou , Naveen Ramesh , Min Hu , Jeffrey Gaither , Danielle Mouhlas , Sayaka Hashimoto , Maggie Humphrey , Theodora Matthews , Jesse M Hunter , Shalini Reshmi , Matthew Schultz , Kristy Lee , Ruthann Pfau , Catherine Cottrell , Kim L McBride , Nicholas E Navin , Bimal P Chaudhari , Marco L Leung

Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas.

Neuro-oncology

Avec: Pravesh Gupta , Minghao Dang , Shivangi Oberai , Simona Migliozzi , Rakesh Trivedi , Gayatri Kumar , Mekenzie Peshoff , Nancy Milam , Aml Ahmed , Krishna Bojja , Tuan M Tran , Joy Gumin , Carlos Kamiya-Matsuoka , Jason Huse , Kathryn Cox , Jianzhuo Li , Huma Shehwana , Sameer A Sheth , Rodriguez Saxon , Sun Baohua , Brittany Parker-Kerrigan , Atul Maheshwari , Edwin Roger Parra Cuentas , Nicholas E Navin , Amy B Heimberger , Frederick F Lang , Antonio Iavarone , Karen Clise-Dwyer , Linghua Wang , Krishna P Bhat

Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing.

Cell genomics

Avec: Jake Leighton , Min Hu , Emi Sei , Funda Meric-Bernstam , Nicholas E Navin

Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing.

BMC cancer

Avec: Danh D Truong , Salah-Eddine Lamhamedi-Cherradi , Robert W Porter , Sandhya Krishnan , Jyothishmathi Swaminathan , Amber Gibson , Alexander J Lazar , J Andrew Livingston , Vidya Gopalakrishnan , Nancy Gordon , Najat C Daw , Nicholas E Navin , Richard Gorlick , Joseph A Ludwig

Réseau de co-auteurs

Emi Sei 10 collaborations

Min Hu 7 collaborations

Shanshan Bai 6 collaborations

Aislyn Schalck 4 collaborations

Karen Clise-Dwyer 3 collaborations

Naveen Ramesh 3 collaborations

Amado J Zurita 3 collaborations

Esther H Lips 3 collaborations

Tapsi Kumar 3 collaborations

Anna K Casasent 3 collaborations

E Shelley Hwang 3 collaborations

None None 3 collaborations

Alastair M Thompson 3 collaborations

Jelle Wesseling 3 collaborations

Alexander Davis 3 collaborations

Kaile Wang 3 collaborations

Michael Kim 2 collaborations

Yuehui Zhao 2 collaborations

Christopher Logothetis 2 collaborations

Vandna Shah 2 collaborations

Lorraine M King 2 collaborations

Petra Kristel 2 collaborations

Jeffrey R Marks 2 collaborations

Deborah Collyar 2 collaborations

Serena Nik-Zainal 2 collaborations

Ruli Gao 2 collaborations

Hui Chen 2 collaborations

Bora Lim 2 collaborations

Funda Meric-Bernstam 2 collaborations

Yun Yan 2 collaborations

Ken Chen 2 collaborations

Jianzhuo Li 2 collaborations

Tuan M Tran 2 collaborations

Zhenna Xiao 2 collaborations

Teresa Manzo 1 collaboration

Boone M Prentice 1 collaboration

Kristin G Anderson 1 collaboration

Ayush Raman 1 collaboration

Gabriela S Codreanu 1 collaboration

Carina B Nava Lauson 1 collaboration

Silvia Tiberti 1 collaboration

Andrea Raimondi 1 collaboration

Marissa A Jones 1 collaboration

Michelle Reyzer 1 collaboration

Breanna M Bates 1 collaboration

Jeffrey M Spraggins 1 collaboration

Nathan H Patterson 1 collaboration

John A McLean 1 collaboration

Kunal Rai 1 collaboration

Carlo Tacchetti 1 collaboration

Sara Tucci 1 collaboration

Jennifer A Wargo 1 collaboration

Simona Rodighiero 1 collaboration

Stacy D Sherrod 1 collaboration

Richard M Caprioli 1 collaboration

Philip D Greenberg 1 collaboration

Giulio Draetta 1 collaboration

Luigi Nezi 1 collaboration

Pei Ching Tsai 1 collaboration

Patricia Troncoso 1 collaboration

Paul G Corn 1 collaboration

Pat Gulhati 1 collaboration

Shan Jiang 1 collaboration

Xiaoying Shang 1 collaboration

Chang-Jiun Wu 1 collaboration

Pingping Hou 1 collaboration

Sharia Hernandez Ruiz 1 collaboration

Luisa Solis Soto 1 collaboration

Edwin Parra 1 collaboration

Haoqiang Ying 1 collaboration

Jincheng Han 1 collaboration

Prasenjit Dey 1 collaboration

Jun Li 1 collaboration

Pingna Deng 1 collaboration

Dean Y Maeda 1 collaboration

John A Zebala 1 collaboration

Denise J Spring 1 collaboration

Huamin Wang 1 collaboration

Anirban Maitra 1 collaboration

Dirk Moore 1 collaboration

Y Alan Wang 1 collaboration

Ronald A DePinho 1 collaboration

Paymaneh D Malihi 1 collaboration

Ryon P Graf 1 collaboration

Angel Rodriguez 1 collaboration

Jerry Lee 1 collaboration

Ramsay Sutton 1 collaboration

Rhett Jiles 1 collaboration

Carmen Ruiz Velasco 1 collaboration

Anand Kolatkar 1 collaboration

Paul Corn 1 collaboration

Ana M Aparicio 1 collaboration

Ryan Dittamore 1 collaboration

James Hicks 1 collaboration

Peter Kuhn 1 collaboration

Anargyros Megalios 1 collaboration

Lindy L Visser 1 collaboration

Michael Sheinman 1 collaboration

Angelo Fortunato 1 collaboration

Marlous Hoogstraat 1 collaboration

Diego Mallo 1 collaboration

Maria Roman-Escorza 1 collaboration

Ahmed A Ahmed 1 collaboration

Mingchu Xu 1 collaboration

Alexandra W van den Belt-Dusebout 1 collaboration

Wim Brugman 1 collaboration

Karen Clements 1 collaboration

Helen R Davies 1 collaboration

Liping Fu 1 collaboration

Anita Grigoriadis 1 collaboration

Timothy M Hardman 1 collaboration

Marielle Krete 1 collaboration

Michiel de Maaker 1 collaboration

Carlo C Maley 1 collaboration

Brian A Menegaz 1 collaboration

Lennart Mulder 1 collaboration

Frank Nieboer 1 collaboration

Salpie Nowinski 1 collaboration

Sarah Pinder 1 collaboration

Jelmar Quist 1 collaboration

Carolina Salinas-Souza 1 collaboration

Michael Schaapveld 1 collaboration

Marjanka K Schmidt 1 collaboration

Abeer M Shaaban 1 collaboration

Rana Shami 1 collaboration

Mathini Sridharan 1 collaboration

John Zhang 1 collaboration

Hilary Stobart 1 collaboration

Lodewyk F A Wessels 1 collaboration

P Andrew Futreal 1 collaboration

Elinor J Sawyer 1 collaboration

Darlan C Minussi 1 collaboration

Michael D Nicholson 1 collaboration

Hanghui Ye 1 collaboration

Toby Baker 1 collaboration

Maxime Tarabichi 1 collaboration

Haowei Du 1 collaboration

Mashiat Rabbani 1 collaboration

Cheng Peng 1 collaboration

Yu-Wei Lin 1 collaboration

Asha Multani 1 collaboration

Jin Ma 1 collaboration

Thomas O McDonald 1 collaboration

Anna Casasent 1 collaboration

Angelica Barrera 1 collaboration

Banu Arun 1 collaboration

Peter Van Loo 1 collaboration

Franziska Michor 1 collaboration

Ying C Henderson 1 collaboration

Yiyun Lin 1 collaboration

Fang Wang 1 collaboration

Simona F Shaitelman 1 collaboration

Jennifer Rui Wang 1 collaboration

Stacy Moulder 1 collaboration

Stephen Y Lai 1 collaboration

Runmin Wei 1 collaboration

Siyuan He 1 collaboration

Alastair Thompson 1 collaboration

Savitri Krishnamurthy 1 collaboration

Mathilde M Almekinders 1 collaboration

Charlotta Mulder 1 collaboration

Proteeti Bhattacharjee 1 collaboration

Jos Jonkers 1 collaboration

Jacco van Rheenen 1 collaboration

Jovanka Gencel-Augusto 1 collaboration

Xiaoping Su 1 collaboration

Yuan Qi 1 collaboration

Elizabeth M Whitley 1 collaboration

Vinod Pant 1 collaboration

Shunbin Xiong 1 collaboration

Vrutant Shah 1 collaboration

Jerome Lin 1 collaboration

Encarnacion Perez 1 collaboration

Marta L Fiorotto 1 collaboration

Iqbal Mahmud 1 collaboration

Abhinav K Jain 1 collaboration

Philip L Lorenzi 1 collaboration

Ellen R Richie 1 collaboration

Guillermina Lozano 1 collaboration

Junke Wang 1 collaboration

Darlan Conterno Minussi 1 collaboration

Aatish Thennavan 1 collaboration

Lei Yang 1 collaboration

Carolien L van der Borden 1 collaboration

Ana Aparicio 1 collaboration

Brian Chapin 1 collaboration

Jie Ye 1 collaboration

Jianjun Zhang 1 collaboration

Don L Gibbons 1 collaboration

Ellinor Sawyer 1 collaboration

Andrew Futreal 1 collaboration

Kevin C Johnson 1 collaboration

Kevin J Anderson 1 collaboration

Elise T Courtois 1 collaboration

Amit D Gujar 1 collaboration

Floris P Barthel 1 collaboration

Frederick S Varn 1 collaboration

Diane Luo 1 collaboration

Martine Seignon 1 collaboration

Eunhee Yi 1 collaboration

Hoon Kim 1 collaboration

Marcos R H Estecio 1 collaboration

Dacheng Zhao 1 collaboration

Ming Tang 1 collaboration

Rahul Maurya 1 collaboration

Chew Yee Ngan 1 collaboration

Niels Verburg 1 collaboration

Philip C de Witt Hamer 1 collaboration

Ketan Bulsara 1 collaboration

Michael L Samuels 1 collaboration

Sunit Das 1 collaboration

Paul Robson 1 collaboration

Roel G W Verhaak 1 collaboration

Rui Ye 1 collaboration

Yawei Qiao 1 collaboration

Steven H Lin 1 collaboration

Mariam T Mathew 1 collaboration

Austin Antoniou 1 collaboration

Jeffrey Gaither 1 collaboration

Danielle Mouhlas 1 collaboration

Sayaka Hashimoto 1 collaboration

Maggie Humphrey 1 collaboration

Theodora Matthews 1 collaboration

Jesse M Hunter 1 collaboration

Shalini Reshmi 1 collaboration

Matthew Schultz 1 collaboration

Kristy Lee 1 collaboration

Ruthann Pfau 1 collaboration

Catherine Cottrell 1 collaboration

Kim L McBride 1 collaboration

Bimal P Chaudhari 1 collaboration

Marco L Leung 1 collaboration

Pravesh Gupta 1 collaboration

Minghao Dang 1 collaboration

Shivangi Oberai 1 collaboration

Simona Migliozzi 1 collaboration

Rakesh Trivedi 1 collaboration

Gayatri Kumar 1 collaboration

Mekenzie Peshoff 1 collaboration

Nancy Milam 1 collaboration

Aml Ahmed 1 collaboration

Krishna Bojja 1 collaboration

Joy Gumin 1 collaboration

Carlos Kamiya-Matsuoka 1 collaboration

Jason Huse 1 collaboration

Kathryn Cox 1 collaboration

Huma Shehwana 1 collaboration

Sameer A Sheth 1 collaboration

Rodriguez Saxon 1 collaboration

Sun Baohua 1 collaboration

Brittany Parker-Kerrigan 1 collaboration

Atul Maheshwari 1 collaboration

Edwin Roger Parra Cuentas 1 collaboration

Amy B Heimberger 1 collaboration

Frederick F Lang 1 collaboration

Antonio Iavarone 1 collaboration

Linghua Wang 1 collaboration

Krishna P Bhat 1 collaboration

Jake Leighton 1 collaboration

Danh D Truong 1 collaboration

Salah-Eddine Lamhamedi-Cherradi 1 collaboration

Robert W Porter 1 collaboration

Sandhya Krishnan 1 collaboration

Jyothishmathi Swaminathan 1 collaboration

Amber Gibson 1 collaboration

Alexander J Lazar 1 collaboration

J Andrew Livingston 1 collaboration

Vidya Gopalakrishnan 1 collaboration

Nancy Gordon 1 collaboration

Najat C Daw 1 collaboration

Richard Gorlick 1 collaboration

Joseph A Ludwig 1 collaboration