Monte Carlo calculation of perturbation correction factors for air-filled ionization chambers in clinical proton beams using TOPAS/GEANT.

Dosimetry Geant4 Monte Carlo Proton therapy TOPAS perturbation correction factors

Journal

Zeitschrift fur medizinische Physik
ISSN: 1876-4436
Titre abrégé: Z Med Phys
Pays: Germany
ID NLM: 100886455

Informations de publication

Date de publication:
May 2021
Historique:
received: 29 02 2020
revised: 20 08 2020
accepted: 31 08 2020
pubmed: 30 3 2021
medline: 29 10 2021
entrez: 29 3 2021
Statut: ppublish

Résumé

Current dosimetry protocols for clinical protons using air-filled ionization chambers assume that the perturbation correction factor is equal to unity for all ionization chambers and proton energies. Since previous Monte Carlo based studies suggest that perturbation correction factors might be significantly different from unity this study aims to determine perturbation correction factors for six plane-parallel and four cylindrical ionization chambers in proton beams at clinical energies. The dose deposited in the air cavity of the ionization chambers was calculated with the help of the Monte Carlo code TOPAS/Geant4 while specific constructive details of the chambers were removed step by step. By comparing these dose values the individual perturbation correction factors p The total perturbation correction factor p Perturbation correction factors for ionization chambers in proton beams were calculated using Monte Carlo simulations. In contrast to the assumption of current dosimetry protocols the total perturbation correction factor p

Identifiants

pubmed: 33775521
pii: S0939-3889(20)30094-5
doi: 10.1016/j.zemedi.2020.08.004
pii:
doi:

Substances chimiques

Protons 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

175-191

Informations de copyright

Copyright © 2020. Published by Elsevier GmbH.

Auteurs

Kilian-Simon Baumann (KS)

University Medical Center Giessen-Marburg, Department of Radiotherapy and Radiooncology, Marburg, Germany; University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany; Marburg Ion-Beam Therapy Center (MIT), Marburg, Germany. Electronic address: kilian-simon.baumann@staff.uni-marburg.de.

Sina Kaupa (S)

University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany.

Constantin Bach (C)

University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany.

Rita Engenhart-Cabillic (R)

University Medical Center Giessen-Marburg, Department of Radiotherapy and Radiooncology, Marburg, Germany; Marburg Ion-Beam Therapy Center (MIT), Marburg, Germany.

Klemens Zink (K)

University Medical Center Giessen-Marburg, Department of Radiotherapy and Radiooncology, Marburg, Germany; University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany; Marburg Ion-Beam Therapy Center (MIT), Marburg, Germany; Frankfurt Institute of Advanced Studies - FIAS, Frankfurt, Germany.

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Classifications MeSH