An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.

Adult Aged Aged, 80 and over COVID-19 / immunology Coculture Techniques / methods Female Humans Immunity, Cellular / immunology Inflammation Mediators / immunology Macrophages / immunology Male Middle Aged Myocardium / immunology Myocytes, Cardiac / immunology Pluripotent Stem Cells / immunology Sequence Analysis, RNA / methods
autopsy drug evaluation, preclinical inflammation myocytes, cardiac pyrimidines

Journal

Circulation research
ISSN: 1524-4571
Titre abrégé: Circ Res
Pays: United States
ID NLM: 0047103

Informations de publication

Date de publication:
25 06 2021
Historique:
pubmed: 16 4 2021
medline: 3 7 2021
entrez: 15 4 2021
Statut: ppublish

Résumé

[Figure: see text].

Identifiants

DOI: 10.1161/CIRCRESAHA.121.319060 PMID: 33853355 PMC: PMC8225586
pubmed: 33853355
doi: 10.1161/CIRCRESAHA.121.319060
pmc: PMC8225586
mid: NIHMS1695154
doi:

Substances chimiques

Inflammation Mediators 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

33-46

Subventions

Organisme : NIDDK NIH HHS
ID : DP3 DK111907
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL135778
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK119667
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA234614
Pays : United States
Organisme : NIDDK NIH HHS
ID : R03 DK117252
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK116075
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK121072
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI107301
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK124463
Pays : United States
Organisme : NHLBI NIH HHS
ID : F31 HL149295
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK127777
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI149033
Pays : United States

Commentaires et corrections

Type : CommentIn

Références

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Auteurs

Liuliu Yang (L)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

Yuling Han (Y)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

Fabrice Jaffré (F)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

Benjamin E Nilsson-Payant (BE)

Department of Microbiology (B.E.N.-P., S.U., J.K.L., B.R.t.), Icahn School of Medicine at Mount Sinai, New York, NY.

Yaron Bram (Y)

Division of Gastroenterology and Hepatology, Department of Medicine (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.
Department of Physiology, Biophysics and Systems Biology (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.

Pengfei Wang (P)

Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY (P.W., Y. Huang, D.D.H.).

Jiajun Zhu (J)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

Tuo Zhang (T)

Genomics Resources Core Facility (T.Z., J.X.), Weill Cornell Medicine, New York, NY.

David Redmond (D)

Division of Regenerative Medicine, Ansary Stem Cell Institute (D.R., S.H.), Weill Cornell Medicine, New York, NY.

Sean Houghton (S)

Division of Regenerative Medicine, Ansary Stem Cell Institute (D.R., S.H.), Weill Cornell Medicine, New York, NY.

Skyler Uhl (S)

Department of Microbiology (B.E.N.-P., S.U., J.K.L., B.R.t.), Icahn School of Medicine at Mount Sinai, New York, NY.

Alain Borczuk (A)

Department of Pathology and Laboratory Medicine (A.B.), Weill Cornell Medicine, New York, NY.

Yaoxing Huang (Y)

Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY (P.W., Y. Huang, D.D.H.).

Chanel Richardson (C)

Division of Gastroenterology and Hepatology, Department of Medicine (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.
Department of Physiology, Biophysics and Systems Biology (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.

Vasuretha Chandar (V)

Division of Gastroenterology and Hepatology, Department of Medicine (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.
Department of Physiology, Biophysics and Systems Biology (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.

Joshua A Acklin (JA)

Graduate School of Biomedical Sciences (J.A.A.), Icahn School of Medicine at Mount Sinai, New York, NY.

Jean K Lim (JK)

Department of Microbiology (B.E.N.-P., S.U., J.K.L., B.R.t.), Icahn School of Medicine at Mount Sinai, New York, NY.

Zhengming Chen (Z)

Department of Population Health Sciences (Z.C.), Weill Cornell Medicine, New York, NY.

Jenny Xiang (J)

Genomics Resources Core Facility (T.Z., J.X.), Weill Cornell Medicine, New York, NY.

David D Ho (DD)

Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY (P.W., Y. Huang, D.D.H.).

Benjamin R tenOever (BR)

Department of Microbiology (B.E.N.-P., S.U., J.K.L., B.R.t.), Icahn School of Medicine at Mount Sinai, New York, NY.

Robert E Schwartz (RE)

Division of Gastroenterology and Hepatology, Department of Medicine (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.
Department of Physiology, Biophysics and Systems Biology (Y.B., C.R., V.C., R.E.S.), Weill Cornell Medicine, New York, NY.

Todd Evans (T)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

Shuibing Chen (S)

Department of Surgery (L.Y., Y. Han, F.J., J.Z., T.E., S.C.), Weill Cornell Medicine, New York, NY.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › An Immuno-Cardiac Model for...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › An Immuno-Cardiac Model for...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › An Immuno-Cardiac Model for...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › An Immuno-Cardiac Model for...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de coculture › An Immuno-Cardiac Model for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › An Immuno-Cardiac Model for...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Immunité cellulaire › An Immuno-Cardiac Model for...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › An Immuno-Cardiac Model for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › An Immuno-Cardiac Model for...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › An Immuno-Cardiac Model for...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › An Immuno-Cardiac Model for...
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › An Immuno-Cardiac Model for...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches pluripotentes › An Immuno-Cardiac Model for...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ARN › An Immuno-Cardiac Model for...