Structural Investigation and Molecular Modeling Studies of Strobilurin-Based Fungicides Active against the Rice Blast Pathogen
antifungal compounds
crop protection
cytochrome bc1 complex
homology modeling
molecular docking
rice blast
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
02 Apr 2021
02 Apr 2021
Historique:
received:
22
02
2021
revised:
27
03
2021
accepted:
01
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
19
5
2021
Statut:
epublish
Résumé
The increasing emergence of fungicide-resistant pathogens requires urgent solutions for crop disease management. Here, we describe a structural investigation of new fungicides obtained by combining strobilurin and succinate dehydrogenase inhibitor pharmacophores. We identified compounds endowed with very good activity against wild-type
Identifiants
pubmed: 33918510
pii: ijms22073731
doi: 10.3390/ijms22073731
pmc: PMC8038316
pii:
doi:
Substances chimiques
Fungicides, Industrial
0
Strobilurins
0
Succinate Dehydrogenase
EC 1.3.99.1
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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