Expression, regulation and clinical significance of B7-H3 on neutrophils in human gastric cancer.
Adult
Aged
B7 Antigens
/ metabolism
Carcinoma
/ metabolism
Disease Progression
Female
Granulocyte-Macrophage Colony-Stimulating Factor
/ metabolism
Humans
In Vitro Techniques
Intercellular Adhesion Molecule-1
/ metabolism
Janus Kinases
/ drug effects
Lymphocytes, Tumor-Infiltrating
/ metabolism
Male
Middle Aged
Neutrophil Activation
Neutrophils
/ drug effects
Prognosis
STAT3 Transcription Factor
/ drug effects
Signal Transduction
Stomach Neoplasms
/ metabolism
Survival Rate
Young Adult
B7-H3
Gastric cancer
Granulocyte-macrophage colony stimulating factor
Neutrophils
Journal
Clinical immunology (Orlando, Fla.)
ISSN: 1521-7035
Titre abrégé: Clin Immunol
Pays: United States
ID NLM: 100883537
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
30
12
2020
revised:
27
04
2021
accepted:
30
04
2021
pubmed:
5
5
2021
medline:
27
7
2021
entrez:
4
5
2021
Statut:
ppublish
Résumé
Neutrophils are conspicuous components of gastric cancer (GC) tumors, increasing with tumor progression and poor patient survival. However, the phenotype, regulation and clinical relevance of neutrophils in human GC are presently unknown. Most intratumoral neutrophils showed an activated CD54
Identifiants
pubmed: 33945871
pii: S1521-6616(21)00090-5
doi: 10.1016/j.clim.2021.108753
pii:
doi:
Substances chimiques
B7 Antigens
0
CD276 protein, human
0
STAT3 Transcription Factor
0
Intercellular Adhesion Molecule-1
126547-89-5
Granulocyte-Macrophage Colony-Stimulating Factor
83869-56-1
Janus Kinases
EC 2.7.10.2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
108753Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.