Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada.
COVID-19
G614D
PANGOLIN lineage
SARS-CoV-2
epidemiology
genetics
infectious disease
public health
Journal
mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533
Informations de publication
Date de publication:
05 05 2021
05 05 2021
Historique:
entrez:
6
5
2021
pubmed:
7
5
2021
medline:
20
5
2021
Statut:
epublish
Résumé
Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions. Here, we review estimates of the genome-wide viral mutation rates, summarize current COVID-19 case load in the province of Ontario, Canada (5 January 2021), and analyze published SARS-CoV-2 genomes from Ontario (collected prior to 24 November 2020) to test for more infectious genetic variants or lineages. The reported mutation rate (∼10
Identifiants
pubmed: 33952657
pii: 6/3/e00011-21
doi: 10.1128/mSphere.00011-21
pmc: PMC8103981
pii:
doi:
Substances chimiques
Spike Glycoprotein, Coronavirus
0
spike protein, SARS-CoV-2
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2021 Sjaarda et al.
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