Control of synthetic microbial consortia in time, space, and composition.

Microbial Consortia Synthetic Biology
control microbial consortia synthetic biology

Journal

Trends in microbiology
ISSN: 1878-4380
Titre abrégé: Trends Microbiol
Pays: England
ID NLM: 9310916

Informations de publication

Date de publication:
12 2021
Historique:
received: 05 02 2021
revised: 02 04 2021
accepted: 07 04 2021
pubmed: 11 5 2021
medline: 8 4 2022
entrez: 10 5 2021
Statut: ppublish

Résumé

While synthetic microbial systems are becoming increasingly complicated, single-strain systems cannot match the complexity of their multicellular counterparts. Such complexity, however, is much more difficult to control. Recent advances have increased our ability to control temporal, spatial, and community compositional organization, including modular adhesive systems, strain growth relationships, and asymmetric cell division. While these systems generally work independently, combining them into unified systems has proven difficult. Once such unification is proven successful we will unlock a new frontier of synthetic biology and open the door to the creation of synthetic biological systems with true multicellularity.

Identifiants

DOI: 10.1016/j.tim.2021.04.001 PMID: 33966922
pubmed: 33966922
pii: S0966-842X(21)00096-2
doi: 10.1016/j.tim.2021.04.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1095-1105

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Nicolas E Grandel (NE)

Graduate Program in Systems, Synthetic, and Physical Biology, Rice University, Houston, TX, USA.

Kiara Reyes Gamas (K)

Graduate Program in Systems, Synthetic, and Physical Biology, Rice University, Houston, TX, USA.

Matthew R Bennett (MR)

Department of Biosciences, Rice University, Houston, TX, USA; Department of Bioengineering, Rice University, Houston, TX, USA. Electronic address: matthew.bennett@rice.edu.

Articles similaires

Minimisation of metabolic networks defines a new functional class of genes.

Giorgio Jansen, Tanda Qi, Vito Latora et al.
1.00
Metabolic Networks and Pathways Saccharomyces cerevisiae Computational Biology Synthetic Biology Computer Simulation

A cross-systems primer for synthetic microbial communities.

Elijah C Mehlferber, Gontran Arnault, Bishnu Joshi et al.
1.00
Microbiota Synthetic Biology Microbial Consortia Humans Microbial Interactions

Community standards and future opportunities for synthetic communities in plant-microbiota research.

Trent R Northen, Manuel Kleiner, Marta Torres et al.
1.00
Plants Microbiota Agriculture Bacteria Synthetic Biology

Mixed and membrane-separated culturing of synthetic cyanobacteria-yeast consortia reveals metabolic cross-talk mimicking natural cyanolichens.

Pavlo Bohutskyi, Kyle R Pomraning, Jackson P Jenkins et al.
1.00
Synechococcus Bioreactors Coculture Techniques Rhodotorula Microbial Consortia

Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Consortiums microbiens › Control of synthetic microbial consortia in...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Biologie synthétique › Control of synthetic microbial consortia in...