Evolutionarily conserved hierarchical gene regulatory networks for plant salt stress response.
Adaptation, Physiological
Arabidopsis
/ genetics
Arabidopsis Proteins
/ genetics
Biological Evolution
Gene Expression Regulation, Plant
Gene Regulatory Networks
Marchantia
/ genetics
Mutation
Oryza
/ genetics
Phylogeny
Plant Proteins
/ genetics
Salt Stress
/ genetics
Transcription Factors
/ genetics
Journal
Nature plants
ISSN: 2055-0278
Titre abrégé: Nat Plants
Pays: England
ID NLM: 101651677
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
19
04
2020
accepted:
23
04
2021
pubmed:
29
5
2021
medline:
17
8
2021
entrez:
28
5
2021
Statut:
ppublish
Résumé
Plant cells constantly alter their gene expression profiles to respond to environmental fluctuations. These continuous adjustments are regulated by multi-hierarchical networks of transcription factors. To understand how such gene regulatory networks (GRNs) have stabilized evolutionarily while allowing for species-specific responses, we compare the GRNs underlying salt response in the early-diverging and late-diverging plants Marchantia polymorpha and Arabidopsis thaliana. Salt-responsive GRNs, constructed on the basis of the temporal transcriptional patterns in the two species, share common trans-regulators but exhibit an evolutionary divergence in cis-regulatory sequences and in the overall network sizes. In both species, WRKY-family transcription factors and their feedback loops serve as central nodes in salt-responsive GRNs. The divergent cis-regulatory sequences of WRKY-target genes are probably associated with the expansion in network size, linking salt stress to tissue-specific developmental and physiological responses. The WRKY modules and highly linked WRKY feedback loops have been preserved widely in other plants, including rice, while keeping their binding-motif sequences mutable. Together, the conserved trans-regulators and the quickly evolving cis-regulatory sequences allow salt-responsive GRNs to adapt over a long evolutionary timescale while maintaining some consistent regulatory structure. This strategy may benefit plants as they adapt to changing environments.
Identifiants
pubmed: 34045707
doi: 10.1038/s41477-021-00929-7
pii: 10.1038/s41477-021-00929-7
doi:
Substances chimiques
Arabidopsis Proteins
0
Plant Proteins
0
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
787-799Références
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