Decoding the molecular mechanism of parthenocarpy in Musa spp. through protein-protein interaction network.
Cytokinins
/ metabolism
Fruit
/ genetics
Gene Expression Regulation, Plant
Gibberellins
/ metabolism
Indoleacetic Acids
/ metabolism
Musa
/ genetics
Parthenogenesis
Plant Growth Regulators
/ metabolism
Plant Proteins
/ genetics
Plants, Genetically Modified
Protein Interaction Maps
Seeds
/ genetics
Signal Transduction
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
16 07 2021
16 07 2021
Historique:
received:
02
03
2021
accepted:
08
06
2021
entrez:
17
7
2021
pubmed:
18
7
2021
medline:
9
11
2021
Statut:
epublish
Résumé
Banana, one of the most important staple fruit among global consumers is highly sterile owing to natural parthenocarpy. Identification of genetic factors responsible for parthenocarpy would facilitate the conventional breeders to improve the seeded accessions. We have constructed Protein-protein interaction (PPI) network through mining differentially expressed genes and the genes used for transgenic studies with respect to parthenocarpy. Based on the topological and pathway enrichment analysis of proteins in PPI network, 12 candidate genes were shortlisted. By further validating these candidate genes in seeded and seedless accession of Musa spp. we put forward MaAGL8, MaMADS16, MaGH3.8, MaMADS29, MaRGA1, MaEXPA1, MaGID1C, MaHK2 and MaBAM1 as possible target genes in the study of natural parthenocarpy. In contrary, expression profile of MaACLB-2 and MaZEP is anticipated to highlight the difference in artificially induced and natural parthenocarpy. By exploring the PPI of validated genes from the network, we postulated a putative pathway that bring insights into the significance of cytokinin mediated CLAVATA(CLV)-WUSHEL(WUS) signaling pathway in addition to gibberellin mediated auxin signaling in parthenocarpy. Our analysis is the first attempt to identify candidate genes and to hypothesize a putative mechanism that bridges the gaps in understanding natural parthenocarpy through PPI network.
Identifiants
pubmed: 34272422
doi: 10.1038/s41598-021-93661-3
pii: 10.1038/s41598-021-93661-3
pmc: PMC8285514
doi:
Substances chimiques
Cytokinins
0
Gibberellins
0
Indoleacetic Acids
0
Plant Growth Regulators
0
Plant Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
14592Informations de copyright
© 2021. The Author(s).
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