[NMR Study of the Discrimination of Enantiomers of Methamphetamine and Its Raw Materials Using Chiral Solvating Agents].
1H-NMR
chiral analysis
chiral solvating agent
ephedrine
methamphetamine
pseudoephedrine
Journal
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
ISSN: 1347-5231
Titre abrégé: Yakugaku Zasshi
Pays: Japan
ID NLM: 0413613
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
2
8
2021
pubmed:
3
8
2021
medline:
28
12
2021
Statut:
ppublish
Résumé
Some controlled substances, such as stimulants and narcotics, have asymmetric carbons in their molecules. Because the enantiomers do not always show the same pharmacological effects, and there are substances with different controls due to differences in their stereochemistry, a simple and unambiguous method for assessment of the composition of enantiomers is necessary. In this study, to develop a simple and rapid stereoscopic identification method for methamphetamine and its raw materials (ephedrine and pseudoephedrine), the
Identifiants
pubmed: 34334549
doi: 10.1248/yakushi.21-00090
doi:
Substances chimiques
BINOL, naphthol
0
Ethers
0
Illicit Drugs
0
Naphthols
0
Phenylacetates
0
Solvents
0
2,2,2-trifluoroethyl allyl ether
1524-54-5
Methamphetamine
44RAL3456C
Mosher's acid
56135-03-6
Pseudoephedrine
7CUC9DDI9F
Chloroform
7V31YC746X
Ephedrine
GN83C131XS
Types de publication
Journal Article
Langues
jpn
Sous-ensembles de citation
IM