Acute Compartment Syndrome of the Upper Extremity in Acquired Hemophilia A: A Case Report and Literature Review.


Journal

JBJS case connector
ISSN: 2160-3251
Titre abrégé: JBJS Case Connect
Pays: United States
ID NLM: 101596828

Informations de publication

Date de publication:
27 08 2021
Historique:
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 5 4 2022
Statut: epublish

Résumé

Acute compartment syndrome (ACS) with acquired hemophilia A (AHA) is rare and has no established treatment strategy. A 64-year-old woman presented with a giant hematoma in the rectus abdominis. Laboratory findings included decreased hemoglobin and increased activated partial thromboplastin time. Arterial embolization was performed for hemostasis. After catheter removal, she developed severe arm pain and numbness with blistering. Fasciotomy was performed to decrease intracompartmental pressure. Laboratory investigations revealed decreased factor VIII (FVIII) activity and increased FVIII inhibitor. AHA was diagnosed and treated with immunosuppressive and FVIII inhibitor-bypassing agents. Fasciotomy should be performed promptly if ACS with AHA is suspected.

Identifiants

pubmed: 34449450
doi: 10.2106/JBJS.CC.21.00304
pii: 01709767-202109000-00094
doi:

Substances chimiques

Factor VIII 9001-27-8

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2021 by The Journal of Bone and Joint Surgery, Incorporated.

Déclaration de conflit d'intérêts

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B649).

Références

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Auteurs

Naoya Inagaki (N)

Department of Orthopaedic Surgery, The Jikei University School of medicine, Tokyo, Japan.

Jun Udaka (J)

Department of Orthopaedic Surgery, The Jikei University School of medicine, Tokyo, Japan.

Kaichi Nishiwaki (K)

Division of Oncology and Hematology, The Jikei University Kashiwa Hospital, Chiba, Japan.

Daiki Hattori (D)

Division of Oncology and Hematology, The Jikei University Kashiwa Hospital, Chiba, Japan.

Yuki Hiramoto (Y)

Department of Surgery, The Jikei University Kashiwa Hospital, Chiba, Japan.

Mitsuru Saito (M)

Department of Orthopaedic Surgery, The Jikei University School of medicine, Tokyo, Japan.

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